Pneumonia — Evaluation of a Disposable Flexible Bronchoscope, aScope IV
Citation(s)
Bellomo R, Tai E, Parkin G Fibreoptic bronchoscopy in the critically ill: a prospective study of its diagnostic and therapeutic value. Anaesth Intensive Care. 1992 Nov;20(4):464-9.
Estella A [Analysis of 208 flexible bronchoscopies performed in an intensive care unit]. Med Intensiva. 2012 Aug-Sep;36(6):396-401. Epub 2011 Dec 20. Spanish.
Pujol E, López AM, Valero R Use of the Ambu(®) aScope™ in 10 patients with predicted difficult intubation. Anaesthesia. 2010 Oct;65(10):1037-40. doi: 10.1111/j.1365-2044.2010.06477.x.
Scutt S, Clark N, Cook TM, Smith C, Christmas T, Coppel L, Crewdson K Evaluation of a single-use intubating videoscope (Ambu aScope ™) in three airway training manikins for oral intubation, nasal intubation and intubation via three supraglottic airway devices. Anaesthesia. 2011 Apr;66(4):293-9. doi: 10.1111/j.1365-2044.2011.06647.x. Epub 2011 Feb 24.
Tsao TC, Tsai YH, Lan RS, Shieh WB, Lee CH Treatment for collapsed lung in critically ill patients. Selective intrabronchial air insufflation using the fiberoptic bronchoscope. Chest. 1990 Feb;97(2):435-8.
Tvede MF, Kristensen MS, Nyhus-Andreasen M A cost analysis of reusable and disposable flexible optical scopes for intubation. Acta Anaesthesiol Scand. 2012 May;56(5):577-84. doi: 10.1111/j.1399-6576.2012.02653.x. Epub 2012 Feb 16.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
