NCT06461884 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Brar NK, Niederman MS
Management of community-acquired pneumonia: a review and update. Ther Adv Respir Dis. 2011 Feb;5(1):61-78. doi: 10.1177/1753465810381518. Epub 2010 Oct 8.
Jackson ML, Neuzil KM, Thompson WW, Shay DK, Yu O, Hanson CA, Jackson LA
The burden of community-acquired pneumonia in seniors: results of a population-based study. Clin Infect Dis. 2004 Dec 1;39(11):1642-50. doi: 10.1086/425615. Epub 2004 Nov 8.
Marchello CS, Ebell MH, Dale AP, Harvill ET, Shen Y, Whalen CC
Signs and Symptoms That Rule out Community-Acquired Pneumonia in Outpatient Adults: A Systematic Review and Meta-Analysis. J Am Board Fam Med. 2019 Mar-Apr;32(2):234-247. doi: 10.3122/jabfm.2019.02.180219.
Miyashita N, Yamauchi Y
Bacterial Pneumonia in Elderly Japanese Populations. Jpn Clin Med. 2018 Jan 3;9:1179670717751433. doi: 10.1177/1179670717751433. eCollection 2018.

Combined Effects of Percussion With Diaphragmatic Breathing Exercises on Airway Clearance in Elderly Pneumonia Patients

Clinical trial NCT06461884 - References