Clinical trial NCT05138484 - References

Periodontal Diseases — Clinical Evaluation of a Mouthwash Containing Malva Sylvestris Extract.

Citation(s)

•   Ainamo J, Bay I
  Problems and proposals for recording gingivitis and plaque. Int Dent J. 1975 Dec;25(4):229-35.
•   Araujo MWB, Charles CA, Weinstein RB, McGuire JA, Parikh-Das AM, Du Q, Zhang J, Berlin JA, Gunsolley JC
  Meta-analysis of the effect of an essential oil-containing mouthrinse on gingivitis and plaque. J Am Dent Assoc. 2015 Aug;146(8):610-622. doi: 10.1016/j.adaj.2015.02.011. Review.
•   Baker K
  Mouthrinses in the prevention and treatment of periodontal disease. Curr Opin Periodontol. 1993:89-96. Review.
•   Barros L, Carvalho AM, Ferreira IC
  Leaves, flowers, immature fruits and leafy flowered stems of Malva sylvestris: a comparative study of the nutraceutical potential and composition. Food Chem Toxicol. 2010 Jun;48(6):1466-72. doi: 10.1016/j.fct.2010.03.012. Epub 2010 Mar 15.
•   Benso B, Franchin M, Massarioli AP, Paschoal JA, Alencar SM, Franco GC, Rosalen PL
  Anti-Inflammatory, Anti-Osteoclastogenic and Antioxidant Effects of Malva sylvestris Extract and Fractions: In Vitro and In Vivo Studies. PLoS One. 2016 Sep 19;11(9):e0162728. doi: 10.1371/journal.pone.0162728. eCollection 2016.
•   Benso B, Rosalen PL, Alencar SM, Murata RM
  Malva sylvestris Inhibits Inflammatory Response in Oral Human Cells. An In Vitro Infection Model. PLoS One. 2015 Oct 19;10(10):e0140331. doi: 10.1371/journal.pone.0140331. eCollection 2015.
•   Collins JR, Olsen J, Cuesta A, Silva-Vetri M, Hernández M, Romanos G, Rajendra Santosh AB, Palma P
  In vitro microbiological analysis on antibacterial, anti-inflammatory, and inhibitory action on matrix metalloproteinases-8 of commercially available chlorhexidine digluconate mouth rinses. Indian J Dent Res. 2018 Nov-Dec;29(6):799-807. doi: 10.4103/ijdr.IJDR_406_17.
•   DellaGreca M, Cutillo F, D'Abrosca B, Fiorentino A, Pacifico S, Zarrelli A
  Antioxidant and radical scavenging properties of Malva sylvestris. Nat Prod Commun. 2009 Jul;4(7):893-6.
•   DRIPPS RD, LAMONT A, ECKENHOFF JE
  The role of anesthesia in surgical mortality. JAMA. 1961 Oct 21;178:261-6.
•   Freires IA, Denny C, Benso B, de Alencar SM, Rosalen PL
  Antibacterial Activity of Essential Oils and Their Isolated Constituents against Cariogenic Bacteria: A Systematic Review. Molecules. 2015 Apr 22;20(4):7329-58. doi: 10.3390/molecules20047329. Review.
•   Gao L, Xu T, Huang G, Jiang S, Gu Y, Chen F
  Oral microbiomes: more and more importance in oral cavity and whole body. Protein Cell. 2018 May;9(5):488-500. doi: 10.1007/s13238-018-0548-1. Epub 2018 May 7. Review.
•   Gasparetto JC, Martins CA, Hayashi SS, Otuky MF, Pontarolo R
  Ethnobotanical and scientific aspects of Malva sylvestris L.: a millennial herbal medicine. J Pharm Pharmacol. 2012 Feb;64(2):172-89. doi: 10.1111/j.2042-7158.2011.01383.x. Epub 2011 Nov 4. Review.
•   Guarrera PM
  Traditional phytotherapy in Central Italy (Marche, Abruzzo, and Latium). Fitoterapia. 2005 Jan;76(1):1-25. Review.
•   Gunsolley JC
  Clinical efficacy of antimicrobial mouthrinses. J Dent. 2010 Jun;38 Suppl 1:S6-10. doi: 10.1016/S0300-5712(10)70004-X. Review.
•   Gürgan CA, Zaim E, Bakirsoy I, Soykan E
  Short-term side effects of 0.2% alcohol-free chlorhexidine mouthrinse used as an adjunct to non-surgical periodontal treatment: a double-blind clinical study. J Periodontol. 2006 Mar;77(3):370-84.
•   Hajishengallis G
  Periodontitis: from microbial immune subversion to systemic inflammation. Nat Rev Immunol. 2015 Jan;15(1):30-44. doi: 10.1038/nri3785. Review.
•   Hooks KB, O'Malley MA
  Dysbiosis and Its Discontents. mBio. 2017 Oct 10;8(5). pii: e01492-17. doi: 10.1128/mBio.01492-17.
•   James P, Worthington HV, Parnell C, Harding M, Lamont T, Cheung A, Whelton H, Riley P
  Chlorhexidine mouthrinse as an adjunctive treatment for gingival health. Cochrane Database Syst Rev. 2017 Mar 31;3:CD008676. doi: 10.1002/14651858.CD008676.pub2. Review.
•   Jeffcoat MK, McGuire M, Newman MG
  Evidence-based periodontal treatment. Highlights from the 1996 World Workshop in Periodontics. J Am Dent Assoc. 1997 Jun;128(6):713-24. Review.
•   Larsen T, Fiehn NE
  Dental biofilm infections - an update. APMIS. 2017 Apr;125(4):376-384. doi: 10.1111/apm.12688. Review.
•   Lazar V, Saviuc CM, Chifiriuc MC
  Periodontitis and Periodontal Disease - Innovative Strategies for Reversing the Chronic Infectious and Inflammatory Condition by Natural Products. Curr Pharm Des. 2016;22(2):230-7. Review.
•   Löe H, Schiött CR, Karring G, Karring T
  Two years oral use of chlorhexidine in man. I. General design and clinical effects. J Periodontal Res. 1976 Jun;11(3):135-44.
•   Löe H
  The Gingival Index, the Plaque Index and the Retention Index Systems. J Periodontol. 1967 Nov-Dec;38(6):Suppl:610-6.
•   Murakami S, Mealey BL, Mariotti A, Chapple ILC
  Dental plaque-induced gingival conditions. J Clin Periodontol. 2018 Jun;45 Suppl 20:S17-S27. doi: 10.1111/jcpe.12937. Review.
•   Newman DJ, Cragg GM
  Natural Products as Sources of New Drugs from 1981 to 2014. J Nat Prod. 2016 Mar 25;79(3):629-61. doi: 10.1021/acs.jnatprod.5b01055. Epub 2016 Feb 7. Review.
•   O'Leary TJ, Drake RB, Naylor JE
  The plaque control record. J Periodontol. 1972 Jan;43(1):38.
•   Offenbacher S, Barros SP, Beck JD
  Rethinking periodontal inflammation. J Periodontol. 2008 Aug;79(8 Suppl):1577-84. doi: 10.1902/jop.2008.080220. Review.
•   Pihlstrom BL, Michalowicz BS, Johnson NW
  Periodontal diseases. Lancet. 2005 Nov 19;366(9499):1809-20. Review.
•   Rafiei M, Kiani F, Sayehmiri F, Sayehmiri K, Sheikhi A, Zamanian Azodi M
  Study of Porphyromonas gingivalis in periodontal diseases: A systematic review and meta-analysis. Med J Islam Repub Iran. 2017 Sep 12;31:62. doi: 10.18869/mjiri.31.62. eCollection 2017.
•   Razavi SM, Zarrini G, Molavi G, Ghasemi G
  Bioactivity of malva sylvestris L., a medicinal plant from iran. Iran J Basic Med Sci. 2011 Nov;14(6):574-9.
•   Tartaglia GM, Kumar S, Fornari CD, Corti E, Connelly ST
  Mouthwashes in the 21(st) century: a narrative review about active molecules and effectiveness on the periodontal outcomes. Expert Opin Drug Deliv. 2017 Aug;14(8):973-982. doi: 10.1080/17425247.2017.1260118. Epub 2016 Nov 20. Review.
•   Teles RP, Teles FR
  Antimicrobial agents used in the control of periodontal biofilms: effective adjuncts to mechanical plaque control? Braz Oral Res. 2009;23 Suppl 1:39-48. Review.
•   Tonetti MS, Greenwell H, Kornman KS
  Staging and grading of periodontitis: Framework and proposal of a new classification and case definition. J Clin Periodontol. 2018 Jun;45 Suppl 20:S149-S161. doi: 10.1111/jcpe.12945. Review. Erratum in: J Clin Periodontol. 2019 Jul;46(7):787.
•   Topcuoglu N, Kulekci G
  16S rRNA based microarray analysis of ten periodontal bacteria in patients with different forms of periodontitis. Anaerobe. 2015 Oct;35(Pt A):35-40. doi: 10.1016/j.anaerobe.2015.01.011. Epub 2015 Jan 29.
•   Van Leeuwen MP, Slot DE, Van der Weijden GA
  Essential oils compared to chlorhexidine with respect to plaque and parameters of gingival inflammation: a systematic review. J Periodontol. 2011 Feb;82(2):174-94. doi: 10.1902/jop.2010.100266. Epub 2010 Nov 2. Review.
•   Van Strydonck DA, Slot DE, Van der Velden U, Van der Weijden F
  Effect of a chlorhexidine mouthrinse on plaque, gingival inflammation and staining in gingivitis patients: a systematic review. J Clin Periodontol. 2012 Nov;39(11):1042-55. doi: 10.1111/j.1600-051X.2012.01883.x. Epub 2012 Sep 7. Review.

Clinical Evaluation of a Mouthwash Containing Malva Sylvestris Extract and Its Role in Reducing Oral Biofilm and Gingival Inflammation. A Randomized, Triple Masked Clinical Trial.

Details for clinical trial NCT05138484