Bellows LL, Davies PL, Anderson J, Kennedy C Effectiveness of a physical activity intervention for Head Start preschoolers: a randomized intervention study. Am J Occup Ther. 2013 Jan-Feb;67(1):28-36. doi: 10.5014/ajot.2013.005777.
Bjork M, Nordstrom B, Hallstrom I Needs of young children with cancer during their initial hospitalization: an observational study. J Pediatr Oncol Nurs. 2006 Jul-Aug;23(4):210-9. doi: 10.1177/1043454206289737.
Bjorklund DF, Brown RD Physical play and cognitive development: integrating activity, cognition, and education. Child Dev. 1998 Jun;69(3):604-6.
Darcy L, Enskar K, Bjork M Young children's experiences of living an everyday life with cancer - A three year interview study. Eur J Oncol Nurs. 2019 Apr;39:1-9. doi: 10.1016/j.ejon.2018.12.007. Epub 2018 Dec 23.
Enright PL The six-minute walk test. Respir Care. 2003 Aug;48(8):783-5.
Faigenbaum AD, Rebullido TR, MacDonald JP Pediatric Inactivity Triad: A Risky PIT. Curr Sports Med Rep. 2018 Feb;17(2):45-47. doi: 10.1249/JSR.0000000000000450. No abstract available.
Gibson F, Aldiss S, Horstman M, Kumpunen S, Richardson A Children and young people's experiences of cancer care: a qualitative research study using participatory methods. Int J Nurs Stud. 2010 Nov;47(11):1397-407. doi: 10.1016/j.ijnurstu.2010.03.019. Epub 2010 Apr 28.
Hansson H, Kjaergaard H, Schmiegelow K, Hallstrom I Hospital-based home care for children with cancer: a qualitative exploration of family members' experiences in Denmark. Eur J Cancer Care (Engl). 2012 Jan;21(1):59-66. doi: 10.1111/j.1365-2354.2011.01280.x. Epub 2011 Aug 18.
Hildenbrand AK, Clawson KJ, Alderfer MA, Marsac ML Coping with pediatric cancer: strategies employed by children and their parents to manage cancer-related stressors during treatment. J Pediatr Oncol Nurs. 2011 Nov-Dec;28(6):344-54. doi: 10.1177/1043454211430823.
Neumann S, Kwisda S, Krettek C, Gaulke R Comparison of the Grip Strength Using the Martin-Vigorimeter and the JAMAR-Dynamometer: Establishment of Normal Values. In Vivo. 2017 Sep-Oct;31(5):917-924. doi: 10.21873/invivo.11147.
Stahlhut M, Christensen J, Aadahl M Applicability and intrarespondent reliability of the pediatric evaluation of disability inventory in a random Danish sample. Pediatr Phys Ther. 2010 Summer;22(2):161-9. doi: 10.1097/PEP.0b013e3181dbf965.
Vannatta K, Gerhardt CA, Wells RJ, Noll RB Intensity of CNS treatment for pediatric cancer: prediction of social outcomes in survivors. Pediatr Blood Cancer. 2007 Oct 15;49(5):716-22. doi: 10.1002/pbc.21062.
Rehabilitation Including Structured Active Play for Preschoolers With Cancer.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
