Pain — The Effect of Mother's Smell and Breast Milk Smell on Pain
Citation(s)
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9 Akcan E. Yenidoganlarda Topuk Kani Alma Sirasinda Olusan Agriya Amniyotik Sivi, Anne Sütü Ve Lavanta Kokusunun Etkisi (tez). Kayseri: Erciyes Üniversitesi; 2014.
Beker F, Opie G, Noble E, Jiang Y, Bloomfield FH Smell and Taste to Improve Nutrition in Very Preterm Infants: A Randomized Controlled Pilot Trial. Neonatology. 2017;111(3):260-266. doi: 10.1159/000450883. Epub 2016 Dec 1.
Cakirli M, Acikgoz A A Randomized Controlled Trial: The Effect of Own Mother's Breast Milk Odor and Another Mother's Breast Milk Odor on Pain Level of Newborn Infants. Breastfeed Med. 2021 Jan;16(1):75-81. doi: 10.1089/bfm.2020.0222. Epub 2020 Oct 20.
Kucuk Alemdar D, Kardas Ozdemir F Effects of Having Preterm Infants Smell Amniotic Fluid, Mother's Milk, and Mother's Odor During Heel Stick Procedure on Pain, Physiological Parameters, and Crying Duration. Breastfeed Med. 2017 Jun;12:297-304. doi: 10.1089/bfm.2017.0006. Epub 2017 Apr 17.
Lan HY, Yang L, Lin CH, Hsieh KH, Chang YC, Yin T Breastmilk as a Multisensory Intervention for Relieving Pain during Newborn Screening Procedures: A Randomized Control Trial. Int J Environ Res Public Health. 2021 Dec 10;18(24):13023. doi: 10.3390/ijerph182413023.
The Effect of Mother's Smell and Breast Milk Smell on Pain and Crying Time During Heel Blood Collection in Newborns
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
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Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
