Clinical trial NCT01398943 - References

Pulmonary Disease, Chronic Obstructive — Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease (COPD)

Citation(s)

•   Anthonisen NR, Connett JE, Enright PL, Manfreda J; Lung Health Study Research Group
  Hospitalizations and mortality in the Lung Health Study. Am J Respir Crit Care Med. 2002 Aug 1;166(3):333-9.
•   Atkinson MH, Ménard HA, Kalish GH
  Assessment of salsalate, a nonacetylated salicylate, in the treatment of patients with arthritis. Clin Ther. 1995 Sep-Oct;17(5):827-37.
•   Bailey DM, Davies B, Young IS, Jackson MJ, Davison GW, Isaacson R, Richardson RS
  EPR spectroscopic detection of free radical outflow from an isolated muscle bed in exercising humans. J Appl Physiol (1985). 2003 May;94(5):1714-8. Epub 2003 Mar 7.
•   Barnes PJ, Karin M
  Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med. 1997 Apr 10;336(15):1066-71. Review.
•   Barr RG, Mesia-Vela S, Austin JH, Basner RC, Keller BM, Reeves AP, Shimbo D, Stevenson L
  Impaired flow-mediated dilation is associated with low pulmonary function and emphysema in ex-smokers: the Emphysema and Cancer Action Project (EMCAP) Study. Am J Respir Crit Care Med. 2007 Dec 15;176(12):1200-7. Epub 2007 Aug 29.
•   Bleeker MW, Kooijman M, Rongen GA, Hopman MT, Smits P
  Preserved contribution of nitric oxide to baseline vascular tone in deconditioned human skeletal muscle. J Physiol. 2005 Jun 1;565(Pt 2):685-94. Epub 2005 Mar 31.
•   Bombardier C, Peloso PM, Goldsmith CH
  Salsalate, a nonacetylated salicylate, is as efficacious as diclofenac in patients with rheumatoid arthritis. Salsalate-Diclofenac Study Group. J Rheumatol. 1995 Apr;22(4):617-24.
•   Casaburi R
  Skeletal muscle function in COPD. Chest. 2000 May;117(5 Suppl 1):267S-71S. Review.
•   Celermajer DS, Adams MR, Clarkson P, Robinson J, McCredie R, Donald A, Deanfield JE
  Passive smoking and impaired endothelium-dependent arterial dilatation in healthy young adults. N Engl J Med. 1996 Jan 18;334(3):150-4.
•   Celermajer DS, Sorensen KE, Georgakopoulos D, Bull C, Thomas O, Robinson J, Deanfield JE
  Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults. Circulation. 1993 Nov;88(5 Pt 1):2149-55.
•   Celermajer DS, Sorensen KE, Gooch VM, Spiegelhalter DJ, Miller OI, Sullivan ID, Lloyd JK, Deanfield JE
  Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis. Lancet. 1992 Nov 7;340(8828):1111-5.
•   Channon KM
  Tetrahydrobiopterin: regulator of endothelial nitric oxide synthase in vascular disease. Trends Cardiovasc Med. 2004 Nov;14(8):323-7. Review.
•   De Boer WI
  Cytokines and therapy in COPD: a promising combination? Chest. 2002 May;121(5 Suppl):209S-218S. Review.
•   Edwards DG, Schofield RS, Lennon SL, Pierce GL, Nichols WW, Braith RW
  Effect of exercise training on endothelial function in men with coronary artery disease. Am J Cardiol. 2004 Mar 1;93(5):617-20.
•   Eickhoff P, Valipour A, Kiss D, Schreder M, Cekici L, Geyer K, Kohansal R, Burghuber OC
  Determinants of systemic vascular function in patients with stable chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2008 Dec 15;178(12):1211-8. doi: 10.1164/rccm.200709-1412OC. Epub 2008 Oct 3.
•   Eskurza I, Myerburgh LA, Kahn ZD, Seals DR
  Tetrahydrobiopterin augments endothelium-dependent dilatation in sedentary but not in habitually exercising older adults. J Physiol. 2005 Nov 1;568(Pt 3):1057-65. Epub 2005 Sep 1.
•   Fukai T
  Endothelial GTPCH in eNOS uncoupling and atherosclerosis. Arterioscler Thromb Vasc Biol. 2007 Jul;27(7):1493-5.
•   Goldfine AB, Silver R, Aldhahi W, Cai D, Tatro E, Lee J, Shoelson SE
  Use of salsalate to target inflammation in the treatment of insulin resistance and type 2 diabetes. Clin Transl Sci. 2008 May;1(1):36-43. doi: 10.1111/j.1752-8062.2008.00026.x.
•   Green D
  Point: Flow-mediated dilation does reflect nitric oxide-mediated endothelial function. J Appl Physiol (1985). 2005 Sep;99(3):1233-4; discussion 1237-8.
•   Guerci B, Kearney-Schwartz A, Böhme P, Zannad F, Drouin P
  Endothelial dysfunction and type 2 diabetes. Part 1: physiology and methods for exploring the endothelial function. Diabetes Metab. 2001 Sep;27(4 Pt 1):425-34. Review.
•   Halliwell B
  Free radicals and antioxidants: a personal view. Nutr Rev. 1994 Aug;52(8 Pt 1):253-65. Review.
•   Harris RA, Nishiyama SK, Wray DW, Tedjasaputra V, Bailey DM, Richardson RS
  The effect of oral antioxidants on brachial artery flow-mediated dilation following 5 and 10 min of ischemia. Eur J Appl Physiol. 2009 Nov;107(4):445-53. doi: 10.1007/s00421-009-1147-x. Epub 2009 Aug 11.
•   Harris RA, Padilla J, Hanlon KP, Rink LD, Wallace JP
  Reproducibility of the flow-mediated dilation response to acute exercise in overweight men. Ultrasound Med Biol. 2007 Oct;33(10):1579-85. Epub 2007 Jun 27.
•   Harris RA, Padilla J, Rink LD, Wallace JP
  Variability of flow-mediated dilation measurements with repetitive reactive hyperemia. Vasc Med. 2006 Feb;11(1):1-6.
•   Heitzer T, Brockhoff C, Mayer B, Warnholtz A, Mollnau H, Henne S, Meinertz T, Münzel T
  Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers : evidence for a dysfunctional nitric oxide synthase. Circ Res. 2000 Feb 4;86(2):E36-41.
•   Keatings VM, Collins PD, Scott DM, Barnes PJ
  Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med. 1996 Feb;153(2):530-4.
•   Khoo JP, Zhao L, Alp NJ, Bendall JK, Nicoli T, Rockett K, Wilkins MR, Channon KM
  Pivotal role for endothelial tetrahydrobiopterin in pulmonary hypertension. Circulation. 2005 Apr 26;111(16):2126-33. Epub 2005 Apr 11.
•   Kingwell BA, Formosa M, Muhlmann M, Bradley SJ, McConell GK
  Nitric oxide synthase inhibition reduces glucose uptake during exercise in individuals with type 2 diabetes more than in control subjects. Diabetes. 2002 Aug;51(8):2572-80.
•   Knowles RG, Moncada S
  Nitric oxide synthases in mammals. Biochem J. 1994 Mar 1;298 ( Pt 2):249-58. Review.
•   Lieberman EH, Gerhard MD, Uehata A, Selwyn AP, Ganz P, Yeung AC, Creager MA
  Flow-induced vasodilation of the human brachial artery is impaired in patients <40 years of age with coronary artery disease. Am J Cardiol. 1996 Dec 1;78(11):1210-4.
•   Macnee W
  Pathogenesis of chronic obstructive pulmonary disease. Clin Chest Med. 2007 Sep;28(3):479-513, v. Review.
•   Maiorana A, O'Driscoll G, Taylor R, Green D
  Exercise and the nitric oxide vasodilator system. Sports Med. 2003;33(14):1013-35. Review.
•   Mercier JG, Hokanson JF, Brooks GA
  Effects of cyclosporine A on skeletal muscle mitochondrial respiration and endurance time in rats. Am J Respir Crit Care Med. 1995 May;151(5):1532-6.
•   Moro L, Pedone C, Scarlata S, Malafarina V, Fimognari F, Antonelli-Incalzi R
  Endothelial dysfunction in chronic obstructive pulmonary disease. Angiology. 2008 Jun-Jul;59(3):357-64. doi: 10.1177/0003319707306141. Epub 2008 Apr 2.
•   Mullen MJ, Kharbanda RK, Cross J, Donald AE, Taylor M, Vallance P, Deanfield JE, MacAllister RJ
  Heterogenous nature of flow-mediated dilatation in human conduit arteries in vivo: relevance to endothelial dysfunction in hypercholesterolemia. Circ Res. 2001 Feb 2;88(2):145-51.
•   Nandi M, Miller A, Stidwill R, Jacques TS, Lam AA, Haworth S, Heales S, Vallance P
  Pulmonary hypertension in a GTP-cyclohydrolase 1-deficient mouse. Circulation. 2005 Apr 26;111(16):2086-90. Epub 2005 Apr 11.
•   Neunteufl T, Kostner K, Katzenschlager R, Zehetgruber M, Maurer G, Weidinger F
  Additional benefit of vitamin E supplementation to simvastatin therapy on vasoreactivity of the brachial artery of hypercholesterolemic men. J Am Coll Cardiol. 1998 Sep;32(3):711-6.
•   Padilla J, Harris RA, Fly AD, Rink LD, Wallace JP
  A comparison between active- and reactive-hyperaemia-induced brachial artery vasodilation. Clin Sci (Lond). 2006 Mar;110(3):387-92.
•   Padilla J, Harris RA, Fly AD, Rink LD, Wallace JP
  The effect of acute exercise on endothelial function following a high-fat meal. Eur J Appl Physiol. 2006 Oct;98(3):256-62. Epub 2006 Aug 3.
•   Pierce GL, Lesniewski LA, Lawson BR, Beske SD, Seals DR
  Nuclear factor-{kappa}B activation contributes to vascular endothelial dysfunction via oxidative stress in overweight/obese middle-aged and older humans. Circulation. 2009 Mar 10;119(9):1284-92. doi: 10.1161/CIRCULATIONAHA.108.804294. Epub 2009 Feb 23.
•   Plantinga Y, Ghiadoni L, Magagna A, Giannarelli C, Franzoni F, Taddei S, Salvetti A
  Supplementation with vitamins C and E improves arterial stiffness and endothelial function in essential hypertensive patients. Am J Hypertens. 2007 Apr;20(4):392-7.
•   Plotnick GD, Corretti MC, Vogel RA
  Effect of antioxidant vitamins on the transient impairment of endothelium-dependent brachial artery vasoactivity following a single high-fat meal. JAMA. 1997 Nov 26;278(20):1682-6.
•   Raitakari OT, Adams MR, McCredie RJ, Griffiths KA, Celermajer DS
  Arterial endothelial dysfunction related to passive smoking is potentially reversible in healthy young adults. Ann Intern Med. 1999 Apr 6;130(7):578-81.
•   Read MA, Whitley MZ, Williams AJ, Collins T
  NF-kappa B and I kappa B alpha: an inducible regulatory system in endothelial activation. J Exp Med. 1994 Feb 1;179(2):503-12.
•   Richardson RS, Secher NH, Tschakovsky ME, Proctor DN, Wray DW
  Metabolic and vascular limb differences affected by exercise, gender, age, and disease. Med Sci Sports Exerc. 2006 Oct;38(10):1792-6.
•   Rubanyi GM, Vanhoutte PM
  Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. Am J Physiol. 1986 May;250(5 Pt 2):H822-7.
•   Sander M, Chavoshan B, Victor RG
  A large blood pressure-raising effect of nitric oxide synthase inhibition in humans. Hypertension. 1999 Apr;33(4):937-42.
•   Schächinger V, Britten MB, Zeiher AM
  Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation. 2000 Apr 25;101(16):1899-906.
•   Selvaraj CL, Gurm HS, Gupta R, Ellis SG, Bhatt DL
  Chronic obstructive pulmonary disease as a predictor of mortality in patients undergoing percutaneous coronary intervention. Am J Cardiol. 2005 Sep 15;96(6):756-9.
•   Shapiro SD, Senior RM
  Matrix metalloproteinases. Matrix degradation and more. Am J Respir Cell Mol Biol. 1999 Jun;20(6):1100-2. Review.
•   Suwaidi JA, Hamasaki S, Higano ST, Nishimura RA, Holmes DR Jr, Lerman A
  Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction. Circulation. 2000 Mar 7;101(9):948-54.
•   Title LM, Cummings PM, Giddens K, Genest JJ Jr, Nassar BA
  Effect of folic acid and antioxidant vitamins on endothelial dysfunction in patients with coronary artery disease. J Am Coll Cardiol. 2000 Sep;36(3):758-65.
•   Tsai WC, Li YH, Lin CC, Chao TH, Chen JH
  Effects of oxidative stress on endothelial function after a high-fat meal. Clin Sci (Lond). 2004 Mar;106(3):315-9.
•   Ueda S, Matsuoka H, Miyazaki H, Usui M, Okuda S, Imaizumi T
  Tetrahydrobiopterin restores endothelial function in long-term smokers. J Am Coll Cardiol. 2000 Jan;35(1):71-5.
•   Uehata A, Lieberman EH, Gerhard MD, Anderson TJ, Ganz P, Polak JF, Creager MA, Yeung AC
  Noninvasive assessment of endothelium-dependent flow-mediated dilation of the brachial artery. Vasc Med. 1997;2(2):87-92.
•   Verma S, Buchanan MR, Anderson TJ
  Endothelial function testing as a biomarker of vascular disease. Circulation. 2003 Oct 28;108(17):2054-9. Review.
•   Vogel RA, Corretti MC, Plotnick GD
  Effect of a single high-fat meal on endothelial function in healthy subjects. Am J Cardiol. 1997 Feb 1;79(3):350-4.
•   Wheatcroft SB, Williams IL, Shah AM, Kearney MT
  Pathophysiological implications of insulin resistance on vascular endothelial function. Diabet Med. 2003 Apr;20(4):255-68. Review.
•   Williams TJ, Howard M, Roget J, Esmore DS
  Exercise capacity after combined heart-lung transplantation. Transplant Proc. 1992 Oct;24(5):2018.
•   Yin MJ, Yamamoto Y, Gaynor RB
  The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Nature. 1998 Nov 5;396(6706):77-80.
•   Zarubina EG, Mishina EA, Osadchuk MA
  [The role of endothelial dysfunction in the pathogenesis of combined cardiopulmonary diseases]. Klin Med (Mosk). 2006;84(5):31-4. Russian.

Regulation of Nitric Oxide Bioavailability in Chronic Obstructive Pulmonary Disease: A Mechanistic Approach

Details for clinical trial NCT01398943