NCT05333523 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

van den Bosch S, Takes RP, de Ridder M, de Bree R, Al-Mamgani A, Schreuder WH, Hoebers FJP, van Weert S, Elbers JBW, Hardillo JA, Meijer TWH, Plaat BEC, de Jong MA, Jansen JC, Wellenstein DJ, van den Broek GB, Vogel WV, Arens AIJ, Kaanders JHAM
Personalized neck irradiation guided by sentinel lymph node biopsy in patients with squamous cell carcinoma of the oropharynx, larynx or hypopharynx with a clinically negative neck: (Chemo)radiotherapy to the PRIMary tumor only. Protocol of the PRIMO study. Clin Transl Radiat Oncol. 2023 Oct 26;44:100696. doi: 10.1016/j.ctro.2023.100696. eCollection 2024 Jan.

Personalized Elective Neck Irradiation Guided by Sentinel Lymph Node Biopsy in Patients With Squamous Cell Carcinoma of the Oropharynx, Larynx or Hypopharynx With a Clinically Negative Neck: (Chemo)Radiotherapy to the PRIMary Tumor Only. The PRIMO Study.

Details for clinical trial NCT05333523

Clinical trial NCT05333523 - References