NCT04289012 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Chan FK, Ching JY, Suen BY, Tse YK, Wu JC, Sung JJ
Effects of Helicobacter pylori infection on long-term risk of peptic ulcer bleeding in low-dose aspirin users. Gastroenterology. 2013 Mar;144(3):528-35. doi: 10.1053/j.gastro.2012.12.038. Epub 2013 Jan 1
Dzierzanowska-Fangrat K, Lehours P, Mégraud F, Dzierzanowska D
Diagnosis of Helicobacter pylori infection. Helicobacter. 2006 Oct;11 Suppl 1:6-13. Review.
Laine L
CLINICAL PRACTICE. Upper Gastrointestinal Bleeding Due to a Peptic Ulcer. N Engl J Med. 2016 Jun 16;374(24):2367-76. doi: 10.1056/NEJMcp1514257. Review.
Malfertheiner P, Megraud F, O'Morain CA, Atherton J, Axon AT, Bazzoli F, Gensini GF, Gisbert JP, Graham DY, Rokkas T, El-Omar EM, Kuipers EJ; European Helicobacter Study Group
Management of Helicobacter pylori infection--the Maastricht IV/ Florence Conse
Sarri GL, Grigg SE, Yeomans ND
Helicobacter pylori and low-dose aspirin ulcer risk: A meta-analysis. J Gastroenterol Hepatol. 2019 Mar;34(3):517-525. doi: 10.1111/jgh.14539. Epub 2018 Dec 17.

HELicobacter Pylori Screening to Prevent Gastrointestinal Bleeding in Patients With Acute Myocardial Infarction Pilot Study

Clinical trial NCT04289012 - References