Human Immunodeficiency Virus Transmission — PC4PrEP: Integrating PrEP Into Primary Care
Citation(s)
Ajzen I, Madden TJ Prediction of goal-directed behavior: attitudes, intentions, and perceived behavioral control. Journal of Experimental Social Psychology. 1986;22(5):453-474
Bronfenbrenner U, Ceci SJ Nature-nurture reconceptualized in developmental perspective: a bioecological model. Psychol Rev. 1994 Oct;101(4):568-86.
Brooks RA, Landovitz RJ, Regan R, Lee SJ, Allen VC Jr Perceptions of and intentions to adopt HIV pre-exposure prophylaxis among black men who have sex with men in Los Angeles. Int J STD AIDS. 2015 Dec;26(14):1040-8. doi: 10.1177/0956462415570159. Epub 2015 Jan 30.
Cáceres CF, O'Reilly KR, Mayer KH, Baggaley R PrEP implementation: moving from trials to policy and practice. J Int AIDS Soc. 2015 Jul 20;18(4 Suppl 3):20222. doi: 10.7448/IAS.18.4.20222. eCollection 2015.
Campbell JD, Herbst JH, Koppenhaver RT, Smith DK Antiretroviral prophylaxis for sexual and injection drug use acquisition of HIV. Am J Prev Med. 2013 Jan;44(1 Suppl 2):S63-9. doi: 10.1016/j.amepre.2012.09.045. Review.
Carlfjord S, Lindberg M, Bendtsen P, Nilsen P, Andersson A Key factors influencing adoption of an innovation in primary health care: a qualitative study based on implementation theory. BMC Fam Pract. 2010 Aug 23;11:60. doi: 10.1186/1471-2296-11-60.
Celum C, Baeten JM Tenofovir-based pre-exposure prophylaxis for HIV prevention: evolving evidence. Curr Opin Infect Dis. 2012 Feb;25(1):51-7. doi: 10.1097/QCO.0b013e32834ef5ef. Review.
Centers for Disease Control and Prevention (CDC) Interim guidance for clinicians considering the use of preexposure prophylaxis for the prevention of HIV infection in heterosexually active adults. MMWR Morb Mortal Wkly Rep. 2012 Aug 10;61(31):586-9.
Centers for Disease Control and Prevention (CDC) Interim guidance: preexposure prophylaxis for the prevention of HIV infection in men who have sex with men. MMWR Morb Mortal Wkly Rep. 2011 Jan 28;60(3):65-8.
Centers for Disease Control and Prevention (CDC) Update to Interim Guidance for Preexposure Prophylaxis (PrEP) for the Prevention of HIV Infection: PrEP for injecting drug users. MMWR Morb Mortal Wkly Rep. 2013 Jun 14;62(23):463-5.
Collins LM, Murphy SA, Strecher V The multiphase optimization strategy (MOST) and the sequential multiple assignment randomized trial (SMART): new methods for more potent eHealth interventions. Am J Prev Med. 2007 May;32(5 Suppl):S112-8.
Cook PF, Friedman R, Lord A, Bradley-Springer LA Outcomes of multimodal training for healthcare professionals at an AIDS education and training center. Eval Health Prof. 2009 Mar;32(1):3-22. doi: 10.1177/0163278708328736. Epub 2009 Jan 8.
Curran GM, Bauer M, Mittman B, Pyne JM, Stetler C Effectiveness-implementation hybrid designs: combining elements of clinical effectiveness and implementation research to enhance public health impact. Med Care. 2012 Mar;50(3):217-26. doi: 10.1097/MLR.0b013e3182408812.
Davis D, O'Brien MA, Freemantle N, Wolf FM, Mazmanian P, Taylor-Vaisey A Impact of formal continuing medical education: do conferences, workshops, rounds, and other traditional continuing education activities change physician behavior or health care outcomes? JAMA. 1999 Sep 1;282(9):867-74.
Drainoni ML, Dekker D, Lee-Hood E, Boehmer U, Relf M HIV medical care provider practices for reducing high-risk sexual behavior: results of a qualitative study. AIDS Patient Care STDS. 2009 May;23(5):347-56. doi: 10.1089/apc.2008.0063.
Eaton LA, Driffin DD, Bauermeister J, Smith H, Conway-Washington C Minimal Awareness and Stalled Uptake of Pre-Exposure Prophylaxis (PrEP) Among at Risk, HIV-Negative, Black Men Who Have Sex with Men. AIDS Patient Care STDS. 2015 Aug;29(8):423-9. doi: 10.1089/apc.2014.0303. Epub 2015 Jun 17.
Flodgren G, Parmelli E, Doumit G, Gattellari M, O'Brien MA, Grimshaw J, Eccles MP Local opinion leaders: effects on professional practice and health care outcomes. Cochrane Database Syst Rev. 2011 Aug 10;(8):CD000125. doi: 10.1002/14651858.CD000125.pub4. Review. Update in: Cochrane Database Syst Rev. 2019 Jun 24;6:CD000125.
Karasz A, Singelis TM Qualitative and Mixed Methods Research in Cross-cultural Psychology: Introduction to the Special Issue. J Cross Cult Psychol. 2009 Nov 1;40(6):909-916.
Karris MY, Beekmann SE, Mehta SR, Anderson CM, Polgreen PM Are we prepped for preexposure prophylaxis (PrEP)? Provider opinions on the real-world use of PrEP in the United States and Canada. Clin Infect Dis. 2014 Mar;58(5):704-12. doi: 10.1093/cid/cit796. Epub 2013 Dec 6.
Koblin B, Chesney M, Coates T; EXPLORE Study Team Effects of a behavioural intervention to reduce acquisition of HIV infection among men who have sex with men: the EXPLORE randomised controlled study. Lancet. 2004 Jul 3-9;364(9428):41-50.
Krakower D, Mayer KH Engaging healthcare providers to implement HIV pre-exposure prophylaxis. Curr Opin HIV AIDS. 2012 Nov;7(6):593-9. doi: 10.1097/COH.0b013e3283590446. Review.
Krakower D, Ware N, Mitty JA, Maloney K, Mayer KH HIV providers' perceived barriers and facilitators to implementing pre-exposure prophylaxis in care settings: a qualitative study. AIDS Behav. 2014 Sep;18(9):1712-21. doi: 10.1007/s10461-014-0839-3.
Levin B The utility of futility. Stroke. 2005 Nov;36(11):2331-2. Epub 2005 Oct 13.
Majumdar SR, Tsuyuki RT, McAlister FA Impact of opinion leader-endorsed evidence summaries on the quality of prescribing for patients with cardiovascular disease: a randomized controlled trial. Am Heart J. 2007 Jan;153(1):22.e1-8.
Mayer KH, Krakower DS Editorial Commentary: Scaling Up Antiretroviral Preexposure Prophylaxis: Moving From Trials to Implementation. Clin Infect Dis. 2015 Nov 15;61(10):1598-600. doi: 10.1093/cid/civ665. Epub 2015 Aug 13.
McDougal SJ, Alexander J, Dhanireddy S, Harrington RD, Stekler JD Non-occupational post-exposure prophylaxis for HIV: 10-year retrospective analysis in Seattle, Washington. PLoS One. 2014 Aug 20;9(8):e105030. doi: 10.1371/journal.pone.0105030. eCollection 2014.
Mimiaga MJ, Case P, Johnson CV, Safren SA, Mayer KH Preexposure antiretroviral prophylaxis attitudes in high-risk Boston area men who report having sex with men: limited knowledge and experience but potential for increased utilization after education. J Acquir Immune Defic Syndr. 2009 Jan 1;50(1):77-83. doi: 10.1097/QAI.0b013e31818d5a27.
Mimiaga MJ, Goldhammer H, Belanoff C, Tetu AM, Mayer KH Men who have sex with men: perceptions about sexual risk, HIV and sexually transmitted disease testing, and provider communication. Sex Transm Dis. 2007 Feb;34(2):113-9.
Mimiaga MJ, White JM, Krakower DS, Biello KB, Mayer KH Suboptimal awareness and comprehension of published preexposure prophylaxis efficacy results among physicians in Massachusetts. AIDS Care. 2014;26(6):684-93. doi: 10.1080/09540121.2013.845289. Epub 2013 Oct 14.
Nadeem E, Olin SS, Hill LC, Hoagwood KE, Horwitz SM Understanding the components of quality improvement collaboratives: a systematic literature review. Milbank Q. 2013 Jun;91(2):354-94. doi: 10.1111/milq.12016. Review.
Nair H, Manchanda P, Bhatia T Asymmetric social interactions in physician prescription behavior: The role of opinion Leaders. Journal of Marketing Research 47(5): 883-895, 2010.
Norton WE, Larson RS, Dearing JW Primary care and public health partnerships for implementing pre-exposure prophylaxis. Am J Prev Med. 2013 Jan;44(1 Suppl 2):S77-9. doi: 10.1016/j.amepre.2012.09.037. Review.
Okun A, Stein RE, Bauman LJ, Silver EJ Content validity of the Psychiatric Symptom Index, CES-depression Scale, and State-Trait Anxiety Inventory from the perspective of DSM-IV. Psychol Rep. 1996 Dec;79(3 Pt 1):1059-69.
Palesch YY, Tilley BC An efficient multi-stage, single-arm Phase II futility design for ALS. Amyotroph Lateral Scler Other Motor Neuron Disord. 2004 Sep;5 Suppl 1:55-6.
Puro V, Palummieri A, De Carli G, Piselli P, Ippolito G Attitude towards antiretroviral Pre-Exposure Prophylaxis (PrEP) prescription among HIV specialists. BMC Infect Dis. 2013 May 14;13:217. doi: 10.1186/1471-2334-13-217.
Smith DK, Pals SL, Herbst JH, Shinde S, Carey JW Development of a clinical screening index predictive of incident HIV infection among men who have sex with men in the United States. J Acquir Immune Defic Syndr. 2012 Aug 1;60(4):421-7. doi: 10.1097/QAI.0b013e318256b2f6.
Stein RE, Bauman LJ, Epstein SG, Gardner JD, Walker DK How well does the questionnaire for identifying children with chronic conditions identify individual children who have chronic conditions? Arch Pediatr Adolesc Med. 2000 May;154(5):447-52.
Stein RE, Westbrook LE, Bauman LJ The Questionnaire for Identifying Children with Chronic Conditions: a measure based on a noncategorical approach. Pediatrics. 1997 Apr;99(4):513-21.
Tellalian D, Maznavi K, Bredeek UF, Hardy WD Pre-exposure prophylaxis (PrEP) for HIV infection: results of a survey of HIV healthcare providers evaluating their knowledge, attitudes, and prescribing practices. AIDS Patient Care STDS. 2013 Oct;27(10):553-9. doi: 10.1089/apc.2013.0173. Epub 2013 Sep 20.
Tripathi A, Ogbuanu C, Monger M, Gibson JJ, Duffus WA Preexposure prophylaxis for HIV infection: healthcare providers' knowledge, perception, and willingness to adopt future implementation in the southern US. South Med J. 2012 Apr;105(4):199-206. doi: 10.1097/SMJ.0b013e31824f1a1b.
Vanable PA, Ostrow DG, McKirnan DJ Viral load and HIV treatment attitudes as correlates of sexual risk behavior among HIV-positive gay men. J Psychosom Res. 2003 Mar;54(3):263-9.
Wheelock A, Eisingerich AB, Gomez GB, Gray E, Dybul MR, Piot P Views of policymakers, healthcare workers and NGOs on HIV pre-exposure prophylaxis (PrEP): a multinational qualitative study. BMJ Open. 2012 Jul 2;2(4). pii: e001234. doi: 10.1136/bmjopen-2012-001234. Print 2012.
White JM, Mimiaga MJ, Krakower DS, Mayer KH Evolution of Massachusetts physician attitudes, knowledge, and experience regarding the use of antiretrovirals for HIV prevention. AIDS Patient Care STDS. 2012 Jul;26(7):395-405. doi: 10.1089/apc.2012.0030. Epub 2012 Jun 13.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.