Clinical trial NCT03076320 - References

Acne Vulgaris Superficial Mixed Comedonal and Inflammatory — Pirfenidone Plus M-DDO Gel in Moderate and Severe Acne

Citation(s)

•   Gollnick HP, Finlay AY, Shear N; Global Alliance to Improve Outcomes in Acne
  Can we define acne as a chronic disease? If so, how and when? Am J Clin Dermatol. 2008;9(5):279-84. doi: 10.2165/00128071-200809050-00001.
•   Holland DB, Jeremy AH
  The role of inflammation in the pathogenesis of acne and acne scarring. Semin Cutan Med Surg. 2005 Jun;24(2):79-83. doi: 10.1016/j.sder.2005.03.004.
•   Kang S, Cho S, Chung JH, Hammerberg C, Fisher GJ, Voorhees JJ
  Inflammation and extracellular matrix degradation mediated by activated transcription factors nuclear factor-kappaB and activator protein-1 in inflammatory acne lesions in vivo. Am J Pathol. 2005 Jun;166(6):1691-9. doi: 10.1016/s0002-9440(10)62479-0.
•   Macias-Barragan J, Sandoval-Rodriguez A, Navarro-Partida J, Armendariz-Borunda J
  The multifaceted role of pirfenidone and its novel targets. Fibrogenesis Tissue Repair. 2010 Sep 1;3:16. doi: 10.1186/1755-1536-3-16.
•   Rodriguez-Castellanos M, Tlacuilo-Parra A, Sanchez-Enriquez S, Velez-Gomez E, Guevara-Gutierrez E
  Pirfenidone gel in patients with localized scleroderma: a phase II study. Arthritis Res Ther. 2015 Jan 28;16(6):510. doi: 10.1186/s13075-014-0510-4.
•   Zhou R, Jiang X
  Effects of adapalene-benzoyl peroxide combination gel in treatment or maintenance therapy of moderate or severe acne vulgaris: a meta-analysis. Ann Dermatol. 2014 Feb;26(1):43-52. doi: 10.5021/ad.2014.26.1.43. Epub 2014 Feb 17.

Molecular and Clinical Study of the Effect of Zaxcell Versus Effezel in the Inflammatory and Scarring Process of Moderate and Severe Acne

Details for clinical trial NCT03076320