Clinical trial NCT02190747 - References

Fibrodysplasia Ossificans Progressiva — An Efficacy and Safety Study of Palovarotene to Treat Preosseous Flare-ups in FOP Subjects

Citation(s)

•   Shimono K, Tung WE, Macolino C, Chi AH, Didizian JH, Mundy C, Chandraratna RA, Mishina Y, Enomoto-Iwamoto M, Pacifici M, Iwamoto M
  Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-? agonists. Nat Med. 2011 Apr;17(4):454-60. doi: 10.1038/nm.2334. Epub 2011 Apr 3. Erratum in: Nat Med. 2012 Oct;18(10):1592.

A Phase 2 Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of a RARγ-Specific Agonist (Palovarotene) in the Treatment of Preosseous Flare-ups in Subjects With Fibrodysplasia Ossificans Progressiva (FOP)

Details for clinical trial NCT02190747