NCT01519115 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Abbott AD, Tyni-Lenné R, Hedlund R
Early rehabilitation targeting cognition, behavior, and motor function after lumbar fusion: a randomized controlled trial. Spine (Phila Pa 1976). 2010 Apr 15;35(8):848-57. doi: 10.1097/BRS.0b013e3181d1049f.
Chiu TT, Law EY, Chiu TH
Performance of the craniocervical flexion test in subjects with and without chronic neck pain. J Orthop Sports Phys Ther. 2005 Sep;35(9):567-71.
Johansson AC, Linton SJ, Bergkvist L, Nilsson O, Cornefjord M
Clinic-based training in comparison to home-based training after first-time lumbar disc surgery: a randomised controlled trial. Eur Spine J. 2009 Mar;18(3):398-409. doi: 10.1007/s00586-008-0826-3. Epub 2008 Nov 20.
O'Leary S, Falla D, Elliott JM, Jull G
Muscle dysfunction in cervical spine pain: implications for assessment and management. J Orthop Sports Phys Ther. 2009 May;39(5):324-33. doi: 10.2519/jospt.2009.2872.
Peolsson A, Kjellman G
Neck muscle endurance in nonspecific patients with neck pain and in patients after anterior cervical decompression and fusion. J Manipulative Physiol Ther. 2007 Jun;30(5):343-50.
Ylinen JJ, Savolainen S, Airaksinen O, Kautiainen H, Salo P, Häkkinen A
Decreased strength and mobility in patients after anterior cervical diskectomy compared with healthy subjects. Arch Phys Med Rehabil. 2003 Jul;84(7):1043-7.

A Comparison of Clinic Outcomes Between Early Physical Therapy Intervention and Usual Care in Individuals Following Anterior Cervical Fusion

Clinical trial NCT01519115 - References