NCT00375154 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Craven RA, Singletary N, Bosken L, Sewell E, Payne M, Lipsey R
Use of bilevel positive airway pressure in out-of-hospital patients. Acad Emerg Med. 2000 Sep;7(9):1065-8.
Thys F, Roeseler J, Delaere S, Palavecino L, El Gariani A, Marion E, Meert P, Danse E, D'Hoore W, Reynaert M
Two-level non-invasive positive pressure ventilation in the initial treatment of acute respiratory failure in an emergency department. Eur J Emerg Med. 1999 Sep;6(3):207-14.
Thys F, Roeseler J, Reynaert M, Liistro G, Rodenstein DO
Noninvasive ventilation for acute respiratory failure: a prospective randomised placebo-controlled trial. Eur Respir J. 2002 Sep;20(3):545-55.
Vanpee D, Delaunois L, Lheureux P, Thys F, Sabbe M, Meulemans A, Stroobants J, Dorio V, Gillet JB
Survey of non-invasive ventilation for acute exacerbation of chronic obstructive pulmonary disease patients in emergency departments in Belgium. Eur J Emerg Med. 2002 Sep;9(3):217-24.

Noninvasive Positive-pressure Ventilation (NPPV) for Acute Respiratory Failure in Out-of-hospital Patients: a Multicenter, Prospective, Randomized Controlled Trial

Details for clinical trial NCT00375154

Clinical trial NCT00375154 - References