Osteoarthritis, Knee — Core Activation and Stabilization for Knee OA
Citation(s)
Al-Zahrani KS, Bakheit AM A study of the gait characteristics of patients with chronic osteoarthritis of the knee. Disabil Rehabil. 2002 Mar 20;24(5):275-80.
Astephen JL, Deluzio KJ, Caldwell GE, Dunbar MJ Biomechanical changes at the hip, knee, and ankle joints during gait are associated with knee osteoarthritis severity. J Orthop Res. 2008 Mar;26(3):332-41.
Chen CP, Chen MJ, Pei YC, Lew HL, Wong PY, Tang SF Sagittal plane loading response during gait in different age groups and in people with knee osteoarthritis. Am J Phys Med Rehabil. 2003 Apr;82(4):307-12.
Duffell LD, Jordan SJ, Cobb JP, McGregor AH Gait adaptations with aging in healthy participants and people with knee-joint osteoarthritis. Gait Posture. 2017 Sep;57:246-251. doi: 10.1016/j.gaitpost.2017.06.015. Epub 2017 Jun 21.
Favre J, Erhart-Hledik JC, Chehab EF, Andriacchi TP Baseline ambulatory knee kinematics are associated with changes in cartilage thickness in osteoarthritic patients over 5 years. J Biomech. 2016 Jun 14;49(9):1859-1864. doi: 10.1016/j.jbiomech.2016.04.029. Epub 2016 Apr 29.
Ferber R, Bolgla L, Earl-Boehm JE, Emery C, Hamstra-Wright K Strengthening of the hip and core versus knee muscles for the treatment of patellofemoral pain: a multicenter randomized controlled trial. J Athl Train. 2015 Apr;50(4):366-77. doi: 10.4085/1062-6050-49.3.70. Epub 2014 Nov 3.
Granacher U, Gollhofer A, Hortobágyi T, Kressig RW, Muehlbauer T The importance of trunk muscle strength for balance, functional performance, and fall prevention in seniors: a systematic review. Sports Med. 2013 Jul;43(7):627-41. doi: 10.1007/s40279-013-0041-1. Review.
Granacher U, Lacroix A, Muehlbauer T, Roettger K, Gollhofer A Effects of core instability strength training on trunk muscle strength, spinal mobility, dynamic balance and functional mobility in older adults. Gerontology. 2013;59(2):105-13. doi: 10.1159/000343152. Epub 2012 Oct 24.
Kumar D, Manal KT, Rudolph KS Knee joint loading during gait in healthy controls and individuals with knee osteoarthritis. Osteoarthritis Cartilage. 2013 Feb;21(2):298-305. doi: 10.1016/j.joca.2012.11.008. Epub 2012 Nov 24.
Linley HS, Sled EA, Culham EG, Deluzio KJ A biomechanical analysis of trunk and pelvis motion during gait in subjects with knee osteoarthritis compared to control subjects. Clin Biomech (Bristol, Avon). 2010 Dec;25(10):1003-10. doi: 10.1016/j.clinbiomech.2010.07.012. Epub 2010 Sep 6.
Menant JC, Schoene D, Sarofim M, Lord SR Single and dual task tests of gait speed are equivalent in the prediction of falls in older people: a systematic review and meta-analysis. Ageing Res Rev. 2014 Jul;16:83-104. doi: 10.1016/j.arr.2014.06.001. Epub 2014 Jun 7. Review.
Messier SP, Loeser RF, Hoover JL, Semble EL, Wise CM Osteoarthritis of the knee: effects on gait, strength, and flexibility. Arch Phys Med Rehabil. 1992 Jan;73(1):29-36. Erratum in: Arch Phys Med Rehabil 1992 Mar;73(3):252.
Messier SP Osteoarthritis of the knee and associated factors of age and obesity: effects on gait. Med Sci Sports Exerc. 1994 Dec;26(12):1446-52. Review.
Whyte EF, Richter C, O'Connor S, Moran KA Effects of a dynamic core stability program on the biomechanics of cutting maneuvers: A randomized controlled trial. Scand J Med Sci Sports. 2018 Feb;28(2):452-462. doi: 10.1111/sms.12931. Epub 2017 Jul 13.
Zazulak BT, Hewett TE, Reeves NP, Goldberg B, Cholewicki J Deficits in neuromuscular control of the trunk predict knee injury risk: a prospective biomechanical-epidemiologic study. Am J Sports Med. 2007 Jul;35(7):1123-30. Epub 2007 Apr 27.
Zeni JA Jr, Higginson JS Differences in gait parameters between healthy subjects and persons with moderate and severe knee osteoarthritis: a result of altered walking speed? Clin Biomech (Bristol, Avon). 2009 May;24(4):372-8. doi: 10.1016/j.clinbiomech.2009.02.001. Epub 2009 Mar 13. Erratum in: Clin Biomech (Bristol, Avon). 2009 Jul;24(6):532.
The Effects of Core Activation and Stabilization Training on Gait Kinetics, Kinematics, and Speed, and Self-Perceived Function in Patients With Knee Osteoarthritis
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.