Osteoarthritis, Knee — Somatosensory Stimulation in Knee Osteoarthritis
Citation(s)
Celnik P, Hummel F, Harris-Love M, Wolk R, Cohen LG Somatosensory stimulation enhances the effects of training functional hand tasks in patients with chronic stroke. Arch Phys Med Rehabil. 2007 Nov;88(11):1369-76.
Courtney CA, O'Hearn MA, Hornby TG Neuromuscular function in painful knee osteoarthritis. Curr Pain Headache Rep. 2012 Dec;16(6):518-24. doi: 10.1007/s11916-012-0299-2. Review.
Herzig D, Maffiuletti NA, Eser P The Application of Neuromuscular Electrical Stimulation Training in Various Non-neurologic Patient Populations: A Narrative Review. PM R. 2015 Nov;7(11):1167-78. doi: 10.1016/j.pmrj.2015.03.022. Epub 2015 Mar 31. Review.
Hortobágyi T, Garry J, Holbert D, Devita P Aberrations in the control of quadriceps muscle force in patients with knee osteoarthritis. Arthritis Rheum. 2004 Aug 15;51(4):562-9.
Kaelin-Lang A Enhancing rehabilitation of motor deficits with peripheral nerve stimulation. NeuroRehabilitation. 2008;23(1):89-93. Review.
Konishi Y, Fukubayashi T, Takeshita D Mechanism of quadriceps femoris muscle weakness in patients with anterior cruciate ligament reconstruction. Scand J Med Sci Sports. 2002 Dec;12(6):371-5.
Palmieri-Smith RM, Thomas AC A neuromuscular mechanism of posttraumatic osteoarthritis associated with ACL injury. Exerc Sport Sci Rev. 2009 Jul;37(3):147-53. doi: 10.1097/JES.0b013e3181aa6669. Review.
Radhakrishnan R, Sluka KA Deep tissue afferents, but not cutaneous afferents, mediate transcutaneous electrical nerve stimulation-Induced antihyperalgesia. J Pain. 2005 Oct;6(10):673-80.
Roos EM, Klässbo M, Lohmander LS WOMAC osteoarthritis index. Reliability, validity, and responsiveness in patients with arthroscopically assessed osteoarthritis. Western Ontario and MacMaster Universities. Scand J Rheumatol. 1999;28(4):210-5.
Roos EM, Toksvig-Larsen S Knee injury and Osteoarthritis Outcome Score (KOOS) - validation and comparison to the WOMAC in total knee replacement. Health Qual Life Outcomes. 2003 May 25;1:17.
Sharma L, Cahue S, Song J, Hayes K, Pai YC, Dunlop D Physical functioning over three years in knee osteoarthritis: role of psychosocial, local mechanical, and neuromuscular factors. Arthritis Rheum. 2003 Dec;48(12):3359-70.
Shirazi ZR, Shafaee R, Abbasi L The effects of transcutaneous electrical nerve stimulation on joint position sense in patients with knee joint osteoarthritis. Physiother Theory Pract. 2014 Oct;30(7):495-9. doi: 10.3109/09593985.2014.903547. Epub 2014 Apr 3.
Tsauo JY, Cheng PF, Yang RS The effects of sensorimotor training on knee proprioception and function for patients with knee osteoarthritis: a preliminary report. Clin Rehabil. 2008 May;22(5):448-57. doi: 10.1177/0269215507084597.
Veldman MP, Zijdewind I, Maffiuletti NA, Hortobágyi T Motor Skill Acquisition and Retention after Somatosensory Electrical Stimulation in Healthy Humans. Front Hum Neurosci. 2016 Mar 16;10:115. doi: 10.3389/fnhum.2016.00115. eCollection 2016.
Wu CW, Seo HJ, Cohen LG Influence of electric somatosensory stimulation on paretic-hand function in chronic stroke. Arch Phys Med Rehabil. 2006 Mar;87(3):351-7.
Somatosensory Electrical Stimulation to Improve Motor Control in Patients Suffering From Knee Osteoarthritis
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
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Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
