NCT05733572 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Abed E, Corbo G, Falsini B
Neurotrophin family members as neuroprotectants in retinal degenerations. BioDrugs. 2015 Feb;29(1):1-13. doi: 10.1007/s40259-014-0110-5.
Chiaretti A, Falsini B, Servidei S, Marangoni D, Pierri F, Riccardi R
Nerve growth factor eye drop administration improves visual function in a patient with optic glioma. Neurorehabil Neural Repair. 2011 May;25(4):386-90. doi: 10.1177/1545968310395601. E
Falsini B, Chiaretti A, Barone G, Piccardi M, Pierri F, Colosimo C, Lazzareschi I, Ruggiero A, Parisi V, Fadda A, Balestrazzi E, Riccardi R
Topical nerve growth factor as a visual rescue strategy in pediatric optic gliomas: a pilot study including electr
Falsini B, Chiaretti A, Rizzo D, Piccardi M, Ruggiero A, Manni L, Soligo M, Dickmann A, Federici M, Salerni A, Timelli L, Guglielmi G, Lazzareschi I, Caldarelli M, Galli-Resta L, Colosimo C, Riccardi R
Nerve growth factor improves visual loss in childhoo

Safety and Efficacy of Multiple Doses of the PAINLESS Nerve Growth Factor CHF6467 in Paediatric Subjects With Optic Pathway Glioma (OPG). A Randomized Clinical Trial (RCT)

Details for clinical trial NCT05733572

Clinical trial NCT05733572 - References