Opioid-Use Disorder (OUD) — SafetyNet Program for Opioid Use Disorder (OUD)
Citation(s)
Amorim P, Lecrubier Y, Weiller E, Hergueta T, Sheehan D DSM-IH-R Psychotic Disorders: procedural validity of the Mini International Neuropsychiatric Interview (MINI). Concordance and causes for discordance with the CIDI. Eur Psychiatry. 1998;13(1):26-34. doi: 10.1016/S0924-9338(97)86748-X.
Capozzi J Heroin epidemic: As deaths rise, program a 'glimmer of hope' for life. myPalmBeachPost. https://www.palmbeachpost.com/news/heroin-epidemic-deaths-rise-program-glimmer-hope-for-life/c8ITU5Q2lJbVFfEjSZKwpK/ (Accessed 01/27/2020)
Dugosh K, Abraham A, Seymour B, McLoyd K, Chalk M, Festinger D A Systematic Review on the Use of Psychosocial Interventions in Conjunction With Medications for the Treatment of Opioid Addiction. J Addict Med. 2016 Mar-Apr;10(2):93-103. doi: 10.1097/ADM.0000000000000193. Review.
Hayes M Fairfield County program targets opioid addiction. This Week Community News; Dec 12, 2017. http://www.thisweeknews.com/news/20171212/fairfield-county-program-targets-opioid-addiction (Accessed 01/27/2020)
Rienzi G Johns Hopkins pilots study on EMS treatment of substance abusers. Johns Hopkins University Gazette. Sept-Oct 2014. https://hub.jhu.edu/gazette/2014/september-october/focus-baltimore-city-ems/ (Accessed 01/27/2020)
Substance Abuse and Mental Health Services Administration SAMHSA's working definition of recovery: 10 guiding principles of recovery. 2012. PEP12-RECDEF https://store.samhsa.gov/system/files/pep12-recdef.pdf (Accessed 1/27/2020)
Tracy K, Wallace SP Benefits of peer support groups in the treatment of addiction. Subst Abuse Rehabil. 2016 Sep 29;7:143-154. eCollection 2016. Review.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
