Clinical trial NCT02499471 - References

Obesity — Brown Adipose Tissue Activity and Thyroid Hormone

Citation(s)

•   Andersen S, Kleinschmidt K, Hvingel B, Laurberg P
  Thyroid hyperactivity with high thyroglobulin in serum despite sufficient iodine intake in chronic cold adaptation in an Arctic Inuit hunter population. Eur J Endocrinol. 2012 Mar;166(3):433-40. doi: 10.1530/EJE-11-0888. Epub 2011 Dec 14.
•   BARKER SB, KLITGAARD HM
  Metabolism of tissues excised from thyroxine-injected rats. Am J Physiol. 1952 Jul;170(1):81-6.
•   Bartelt A, Bruns OT, Reimer R, Hohenberg H, Ittrich H, Peldschus K, Kaul MG, Tromsdorf UI, Weller H, Waurisch C, Eychmüller A, Gordts PL, Rinninger F, Bruegelmann K, Freund B, Nielsen P, Merkel M, Heeren J
  Brown adipose tissue activity controls triglycer
•   Bianco AC, Salvatore D, Gereben B, Berry MJ, Larsen PR
  Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev. 2002 Feb;23(1):38-89. Review.
•   Bilezikian JP, Loeb JN
  The influence of hyperthyroidism and hypothyroidism on alpha- and beta-adrenergic receptor systems and adrenergic responsiveness. Endocr Rev. 1983 Fall;4(4):378-88. Review.
•   Cannon B, Nedergaard J
  Brown adipose tissue: function and physiological significance. Physiol Rev. 2004 Jan;84(1):277-359. Review.
•   Cannon B, Nedergaard J
  Thyroid hormones: igniting brown fat via the brain. Nat Med. 2010 Sep;16(9):965-7. doi: 10.1038/nm0910-965.
•   Castillo M, Hall JA, Correa-Medina M, Ueta C, Kang HW, Cohen DE, Bianco AC
  Disruption of thyroid hormone activation in type 2 deiodinase knockout mice causes obesity with glucose intolerance and liver steatosis only at thermoneutrality. Diabetes. 2011 Ap
•   Danforth E Jr, Burger A
  The role of thyroid hormones in the control of energy expenditure. Clin Endocrinol Metab. 1984 Nov;13(3):581-95. Review.
•   de Jesus LA, Carvalho SD, Ribeiro MO, Schneider M, Kim SW, Harney JW, Larsen PR, Bianco AC
  The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue. J Clin Invest. 2001 Nov;108(9):1379-85.
•   Endo T, Kobayashi T
  Thyroid-stimulating hormone receptor in brown adipose tissue is involved in the regulation of thermogenesis. Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E514-8. doi: 10.1152/ajpendo.90433.2008. Epub 2008 Jun 17.
•   Gagnon A, Antunes TT, Ly T, Pongsuwan P, Gavin C, Lochnan HA, Sorisky A
  Thyroid-stimulating hormone stimulates lipolysis in adipocytes in culture and raises serum free fatty acid levels in vivo. Metabolism. 2010 Apr;59(4):547-53. doi: 10.1016/j.metabol.2
•   Goglia F, Silvestri E, Lanni A
  Thyroid hormones and mitochondria. Biosci Rep. 2002 Feb;22(1):17-32. Review.
•   Johannsen DL, Galgani JE, Johannsen NM, Zhang Z, Covington JD, Ravussin E
  Effect of short-term thyroxine administration on energy metabolism and mitochondrial efficiency in humans. PLoS One. 2012;7(7):e40837. doi: 10.1371/journal.pone.0040837. Epub 2012 Jul 26.
•   Kim MS, Hu HH, Aggabao PC, Geffner ME, Gilsanz V
  Presence of brown adipose tissue in an adolescent with severe primary hypothyroidism. J Clin Endocrinol Metab. 2014 Sep;99(9):E1686-90. doi: 10.1210/jc.2014-1343. Epub 2014 Jun 10.
•   Kingma BR, Frijns AJ, Saris WH, van Steenhoven AA, Lichtenbelt WD
  Increased systolic blood pressure after mild cold and rewarming: relation to cold-induced thermogenesis and age. Acta Physiol (Oxf). 2011 Dec;203(4):419-27. doi: 10.1111/j.1748-1716.2011.02336.x. Epub 2011 Aug 12.
•   Lahesmaa M, Orava J, Schalin-Jäntti C, Soinio M, Hannukainen JC, Noponen T, Kirjavainen A, Iida H, Kudomi N, Enerbäck S, Virtanen KA, Nuutila P
  Hyperthyroidism increases brown fat metabolism in humans. J Clin Endocrinol Metab. 2014 Jan;99(1):E28-35. doi: 10.1210/jc.2013-2312. Epub 2013 Dec 20.
•   Lee JY, Takahashi N, Yasubuchi M, Kim YI, Hashizaki H, Kim MJ, Sakamoto T, Goto T, Kawada T
  Triiodothyronine induces UCP-1 expression and mitochondrial biogenesis in human adipocytes. Am J Physiol Cell Physiol. 2012 Jan 15;302(2):C463-72. doi: 10.1152/ajpcell.00010.2011. Epub 2011 Nov 9.
•   Liu D, Jiang F, Shan Z, Wang B, Wang J, Lai Y, Chen Y, Li M, Liu H, Li C, Xue H, Li N, Yu J, Shi L, Bai X, Hou X, Zhu L, Lu L, Wang S, Xing Q, Teng W
  A cross-sectional survey of relationship between serum TSH level and blood pressure. J Hum Hypertens. 20
•   López M, Varela L, Vázquez MJ, Rodríguez-Cuenca S, González CR, Velagapudi VR, Morgan DA, Schoenmakers E, Agassandian K, Lage R, Martínez de Morentin PB, Tovar S, Nogueiras R, Carling D, Lelliott C, Gallego R, Oresic M, Chatterjee K, Saha AK, Rahmouni K, Diéguez C, Vidal-Puig A
  Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance. Nat Med. 2010 Sep;16(9):1001-8. doi: 10.1038/nm.2207. Epub 2010 Aug 29.
•   Louzada RA, Santos MC, Cavalcanti-de-Albuquerque JP, Rangel IF, Ferreira AC, Galina A, Werneck-de-Castro JP, Carvalho DP
  Type 2 iodothyronine deiodinase is upregulated in rat slow- and fast-twitch skeletal muscle during cold exposure. Am J Physiol Endocrinol Metab. 2014 Dec 1;307(11):E1020-9. doi: 10.1152/ajpendo.00637.2013. Epub 2014 Oct 7.
•   Mokdad AH, Marks JS, Stroup DF, Gerberding JL
  Actual causes of death in the United States, 2000. JAMA. 2004 Mar 10;291(10):1238-45. Review. Erratum in: JAMA. 2005 Jan 19;293(3):298. JAMA. 2005 Jan 19;293(3):293-4.
•   Nedergaard J, Golozoubova V, Matthias A, Asadi A, Jacobsson A, Cannon B
  UCP1: the only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency. Biochim Biophys Acta. 2001 Mar 1;1504(1):82-106. Review.
•   Orava J, Nuutila P, Lidell ME, Oikonen V, Noponen T, Viljanen T, Scheinin M, Taittonen M, Niemi T, Enerbäck S, Virtanen KA
  Different metabolic responses of human brown adipose tissue to activation by cold and insulin. Cell Metab. 2011 Aug 3;14(2):272-9. doi: 10.1016/j.cmet.2011.06.012.
•   Saito M, Okamatsu-Ogura Y, Matsushita M, Watanabe K, Yoneshiro T, Nio-Kobayashi J, Iwanaga T, Miyagawa M, Kameya T, Nakada K, Kawai Y, Tsujisaki M
  High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity. Diabetes. 2009 Jul;58(7):1526-31. doi: 10.2337/db09-0530. Epub 2009 Apr 28.
•   Silva JE, Bianco SD
  Thyroid-adrenergic interactions: physiological and clinical implications. Thyroid. 2008 Feb;18(2):157-65. doi: 10.1089/thy.2007.0252. Review.
•   Skarulis MC, Celi FS, Mueller E, Zemskova M, Malek R, Hugendubler L, Cochran C, Solomon J, Chen C, Gorden P
  Thyroid hormone induced brown adipose tissue and amelioration of diabetes in a patient with extreme insulin resistance. J Clin Endocrinol Metab. 2
•   TATA JR, ERNSTER L, LINDBERG O
  Control of basal metabolic rate by thyroid hormones and cellular function. Nature. 1962 Mar 17;193:1058-60.
•   Thrush AB, Gagnon A, Sorisky A
  PKC activation is required for TSH-mediated lipolysis via perilipin activation. Horm Metab Res. 2012 Oct;44(11):825-31. doi: 10.1055/s-0032-1316332. Epub 2012 Jun 22.
•   van der Lans AA, Hoeks J, Brans B, Vijgen GH, Visser MG, Vosselman MJ, Hansen J, Jörgensen JA, Wu J, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD
  Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. J Clin Invest. 2013 Aug;123(8):3395-403. doi: 10.1172/JCI68993. Epub 2013 Jul 15.
•   van Marken Lichtenbelt WD, Daanen HA, Wouters L, Fronczek R, Raymann RJ, Severens NM, Van Someren EJ
  Evaluation of wireless determination of skin temperature using iButtons. Physiol Behav. 2006 Jul 30;88(4-5):489-97. Epub 2006 Jun 23.
•   van Marken Lichtenbelt WD, Vanhommerig JW, Smulders NM, Drossaerts JM, Kemerink GJ, Bouvy ND, Schrauwen P, Teule GJ
  Cold-activated brown adipose tissue in healthy men. N Engl J Med. 2009 Apr 9;360(15):1500-8. doi: 10.1056/NEJMoa0808718. Erratum in: N Engl J Med. 2009 Apr 30;360(18):1917.
•   Virtanen KA, Lidell ME, Orava J, Heglind M, Westergren R, Niemi T, Taittonen M, Laine J, Savisto NJ, Enerbäck S, Nuutila P
  Functional brown adipose tissue in healthy adults. N Engl J Med. 2009 Apr 9;360(15):1518-25. doi: 10.1056/NEJMoa0808949. Erratum in: N Engl J Med. 2009 Sep 10;361(11):1123.
•   Völzke H, Alte D, Dörr M, Wallaschofski H, John U, Felix SB, Rettig R
  The association between subclinical hyperthyroidism and blood pressure in a population-based study. J Hypertens. 2006 Oct;24(10):1947-53.
•   Vosselman MJ, van der Lans AA, Brans B, Wierts R, van Baak MA, Schrauwen P, van Marken Lichtenbelt WD
  Systemic ß-adrenergic stimulation of thermogenesis is not accompanied by brown adipose tissue activity in humans. Diabetes. 2012 Dec;61(12):3106-13. doi: 10.2337/db12-0288. Epub 2012 Aug 7.

Brown Adipose Tissue Activity and Thyroid Hormone

Details for clinical trial NCT02499471