Clinical trial NCT02048215 - References

Obesity — Effect on Energy Metabolism at Cellular Level of Diet Plus Treatment With Ephedrine and Caffeine in Obesity

Citation(s)

•   Acheson KJ, Zahorska-Markiewicz B, Pittet P, Anantharaman K, Jéquier E
  Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals. Am J Clin Nutr. 1980 May;33(5):989-97.
•   Astrup A, Breum L, Toubro S
  Pharmacological and clinical studies of ephedrine and other thermogenic agonists. Obes Res. 1995 Nov;3 Suppl 4:537S-540S. Review.
•   Astrup A, Toubro S, Christensen NJ, Quaade F
  Pharmacology of thermogenic drugs. Am J Clin Nutr. 1992 Jan;55(1 Suppl):246S-248S. Review.
•   Bellet S, Roman L, DeCastro O, Kim KE, Kershbaum A
  Effect of coffee ingestion on catecholamine release. Metabolism. 1969 Apr;18(4):288-91.
•   Berkowitz BA, Spector S
  Effect of caffeine and theophylline on peripheral catecholamines. Eur J Pharmacol. 1971 Jan;13(2):193-6.
•   De Matteis R, Arch JR, Petroni ML, Ferrari D, Cinti S, Stock MJ
  Immunohistochemical identification of the beta(3)-adrenoceptor in intact human adipocytes and ventricular myocardium: effect of obesity and treatment with ephedrine and caffeine. Int J Obes
•   Dulloo AG, Miller DS
  The thermogenic properties of ephedrine/methylxanthine mixtures: human studies. Int J Obes. 1986;10(6):467-81.
•   Garruti G, Ricquier D
  Analysis of uncoupling protein and its mRNA in adipose tissue deposits of adult humans. Int J Obes Relat Metab Disord. 1992 May;16(5):383-90.
•   Grujic D, Susulic VS, Harper ME, Himms-Hagen J, Cunningham BA, Corkey BE, Lowell BB
  Beta3-adrenergic receptors on white and brown adipocytes mediate beta3-selective agonist-induced effects on energy expenditure, insulin secretion, and food intake. A study using transgenic and gene knockout mice. J Biol Chem. 1997 Jul 11;272(28):17686-93.
•   Klaus S, Casteilla L, Bouillaud F, Ricquier D
  The uncoupling protein UCP: a membraneous mitochondrial ion carrier exclusively expressed in brown adipose tissue. Int J Biochem. 1991;23(9):791-801. Review.
•   Lean ME, James WP, Jennings G, Trayhurn P
  Brown adipose tissue in patients with phaeochromocytoma. Int J Obes. 1986;10(3):219-27.
•   Miller DS, Stock MJ, Stuart JA
  Proceedings: The effects of caffeine and carnitine on the oxygen consumption of fed and fasted subjects. Proc Nutr Soc. 1974 Sep;33(2):28A-29A.
•   Millet L, Vidal H, Andreelli F, Larrouy D, Riou JP, Ricquier D, Laville M, Langin D
  Increased uncoupling protein-2 and -3 mRNA expression during fasting in obese and lean humans. J Clin Invest. 1997 Dec 1;100(11):2665-70.
•   Oberkofler H, Dallinger G, Liu YM, Hell E, Krempler F, Patsch W
  Uncoupling protein gene: quantification of expression levels in adipose tissues of obese and non-obese humans. J Lipid Res. 1997 Oct;38(10):2125-33.
•   Solanes G, Vidal-Puig A, Grujic D, Flier JS, Lowell BB
  The human uncoupling protein-3 gene. Genomic structure, chromosomal localization, and genetic basis for short and long form transcripts. J Biol Chem. 1997 Oct 10;272(41):25433-6.

Evaluation of Diet and Treatment With a Combination of Ephedrine and Caffeine on Thermogenesis, Cardiac Function and on Uncoupling Proteins Expression in Adipose and Muscle Tissue of Morbid Obese Patients Undergoing Bariatric Surgery.

Details for clinical trial NCT02048215