NCT02148614 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Alipour A, Elte JW, van Zaanen HC, Rietveld AP, Castro Cabezas M
Novel aspects of postprandial lipemia in relation to atherosclerosis. Atheroscler Suppl. 2008 Sep;9(2):39-44. doi: 10.1016/j.atherosclerosissup.2008.05.007. Epub 2008 Jul 1. Review.
Maffeis C, Surano MG, Cordioli S, Gasperotti S, Corradi M, Pinelli L
A high-fat vs. a moderate-fat meal in obese boys: nutrient balance, appetite, and gastrointestinal hormone changes. Obesity (Silver Spring). 2010 Mar;18(3):449-55. doi: 10.1038/oby.2009.271. Epub 2009 Aug 27.
Murphy KG, Bloom SR
Gut hormones and the regulation of energy homeostasis. Nature. 2006 Dec 14;444(7121):854-9. Review.
Shay CM, Ning H, Daniels SR, Rooks CR, Gidding SS, Lloyd-Jones DM
Status of cardiovascular health in US adolescents: prevalence estimates from the National Health and Nutrition Examination Surveys (NHANES) 2005-2010. Circulation. 2013 Apr 2;127(13):1369-76. doi: 10.1161/CIRCULATIONAHA.113.001559. Epub 2013 Apr 1.
Verbeke K, Ferchaud-Roucher V, Preston T, Small AC, Henckaerts L, Krempf M, Wang H, Vonk RJ, Priebe MG
Influence of the type of indigestible carbohydrate on plasma and urine short-chain fatty acid profiles in healthy human volunteers. Eur J Clin Nutr. 2010 Jul;64(7):678-84. doi: 10.1038/ejcn.2010.92. Epub 2010 May 26.

Intake of a Polysaccharides Mix (LibraMedR) in Obese Children. 1. Postprandial Effects on Metabolism, Hormones and Satiety; 2. Effects on Body Fat, Glucide and Fat Metabolism After a 60-day Treatment.

Details for clinical trial NCT02148614

Clinical trial NCT02148614 - References