NCT01343017 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Enekvist B, Bodelsson M, Sturesson LW, Johansson A
Larger tidal volume increases sevoflurane uptake in blood: a randomized clinical study. Acta Anaesthesiol Scand. 2010 Oct;54(9):1111-6. doi: 10.1111/j.1399-6576.2010.02291.x.
Enekvist BJ, Luttropp HH, Johansson A
The effect of increased apparatus dead space and tidal volumes on carbon dioxide elimination and oxygen saturations in a low-flow anesthesia system. J Clin Anesth. 2008 May;20(3):170-4. doi: 10.1016/j.jclinane.2007.09.013.
Luttropp HH, Johansson A
Soda lime temperatures during low-flow sevoflurane anaesthesia and differences in dead-space. Acta Anaesthesiol Scand. 2002 May;46(5):500-5.
Sturesson LW, Johansson A, Bodelsson M, Malmkvist G
Wash-in kinetics for sevoflurane using a disposable delivery system (AnaConDa) in cardiac surgery patients. Br J Anaesth. 2009 Apr;102(4):470-6. doi: 10.1093/bja/aep019. Epub 2009 Feb 25.

Increased Tidal Volume During Anaesthesia Compared to PEEP. Impact on Arterial Concentration of Sevoflurane, Oxygenation and Cardiac Output in a Randomised Clinical Study of Overweight Patients.

Details for clinical trial NCT01343017

Clinical trial NCT01343017 - References