NCT05474456 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Ali A, Shakil-Ur-Rehman S, Sibtain F
The efficacy of Sustained Natural Apophyseal Glides with and without Isometric Exercise Training in Non-specific Neck Pain. Pak J Med Sci. 2014 Jul;30(4):872-4.
Clark R, Doyle M, Sybrowsky C, Rosenquist R
Epidural steroid injections for the treatment of cervical radiculopathy in elite wrestlers: case series and literature review. Iowa Orthop J. 2012;32:207-14.
Durall CJ
Therapeutic exercise for athletes with nonspecific neck pain: a current concepts review. Sports Health. 2012 Jul;4(4):293-301. doi: 10.1177/1941738112446138.
Hidalgo B, Hall T, Bossert J, Dugeny A, Cagnie B, Pitance L
The efficacy of manual therapy and exercise for treating non-specific neck pain: A systematic review. J Back Musculoskelet Rehabil. 2017 Nov 6;30(6):1149-1169. doi: 10.3233/BMR-169615.
Moutzouri M, Billis E, Strimpakos N, Kottika P, Oldham JA
The effects of the Mulligan Sustained Natural Apophyseal Glide (SNAG) mobilisation in the lumbar flexion range of asymptomatic subjects as measured by the Zebris CMS20 3-D motion analysis system. BMC Musculoskelet Disord. 2008 Oct 1;9:131. doi: 10.1186/1471-2474-9-131.
Verhagen AP
Physiotherapy management of neck pain. J Physiother. 2021 Jan;67(1):5-11. doi: 10.1016/j.jphys.2020.12.005. Epub 2020 Dec 24. No abstract available.

Effects of Sustained Natural Apophyseal Glides Versus Cervical Manipulation on Pain and Disability in Non Specific Neck Among Wrestlers

Clinical trial NCT05474456 - References