NCT04459195 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Caliskan E, Akkoc O, Bayramoglu Z, Gozubuyuk OB, Kural D, Azamat S, Adaletli I
Effects of static stretching duration on muscle stiffness and blood flow in the rectus femoris in adolescents. Med Ultrason. 2019 May 2;21(2):136-143. doi: 10.11152/mu-1859.
Jiang ZZ, Huang YH, Shen HL, Liu XT
Clinical Applications of Superb Microvascular Imaging in the Liver, Breast, Thyroid, Skeletal Muscle, and Carotid Plaques. J Ultrasound Med. 2019 Nov;38(11):2811-2820. doi: 10.1002/jum.15008. Epub 2019 Apr 5. Review.
Maeda N, Urabe Y, Tsutsumi S, Sakai S, Fujishita H, Kobayashi T, Asaeda M, Hirata K, Mikami Y, Kimura H
The Acute Effects of Static and Cyclic Stretching on Muscle Stiffness and Hardness of Medial Gastrocnemius Muscle. J Sports Sci Med. 2017 Dec 1;16(4):514-520. eCollection 2017 Dec.
Nakamura M, Ikezoe T, Nishishita S, Umehara J, Kimura M, Ichihashi N
Acute effects of static stretching on the shear elastic moduli of the medial and lateral gastrocnemius muscles in young and elderly women. Musculoskelet Sci Pract. 2017 Dec;32:98-103. doi: 10.1016/j.msksp.2017.09.006. Epub 2017 Sep 25.

An Investigation of Acute Effects of Static Stretching Duration on Gastrocnemius Muscle Vascularization by Superb Microvascular Imaging Method

Clinical trial NCT04459195 - References