NCT04737226 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Cristi-Sánchez I, Danes-Daetz C, Neira A, Ferrada W, Yáñez Díaz R, Silvestre Aguirre R
Patellar and Achilles Tendon Stiffness in Elite Soccer Players Assessed Using Myotonometric Measurements. Sports Health. 2019 Mar/Apr;11(2):157-162. doi: 10.1177/1941738118820517. Epub 2019 Jan 2.
Gavronski G, Veraksits A, Vasar E, Maaroos J
Evaluation of viscoelastic parameters of the skeletal muscles in junior triathletes. Physiol Meas. 2007 Jun;28(6):625-37. Epub 2007 May 3.
Kubo K, Miyazaki D, Shimoju S, Tsunoda N
Relationship between elastic properties of tendon structures and performance in long distance runners. Eur J Appl Physiol. 2015 Aug;115(8):1725-33. doi: 10.1007/s00421-015-3156-2. Epub 2015 Mar 27.
Liu CL, Li YP, Wang XQ, Zhang ZJ
Quantifying the Stiffness of Achilles Tendon: Intra- and Inter-Operator Reliability and the Effect of Ankle Joint Motion. Med Sci Monit. 2018 Jul 14;24:4876-4881. doi: 10.12659/MSM.909531.
Pozarowszczyk B, Pawlaczyk W, Smoter M, Zarzycki A, Mroczek D, Kumorek M, Witkowski K, Adam K
Effects of Karate Fights on Achilles Tendon Stiffness Measured by Myotonometry. J Hum Kinet. 2017 Mar 12;56:93-97. doi: 10.1515/hukin-2017-0026. eCollection 2017 Feb.

The Association Between Ankle Mobility and Achilles Tendon, Plantar Fascia, Iliotibial Band Stiffness and Elasticity in Athletes

Clinical trial NCT04737226 - References