Hunter M The women's health Questionnaire: a meassure of mid-aged women's perceptions on their emotional and physical health. Psycol Health 7: 45-54, 1992
Hunter MS, Coventry S, Hamed H, Fentiman I, Grunfeld EA Evaluation of a group cognitive behavioural intervention for women suffering from menopausal symptoms following breast cancer treatment. Psychooncology. 2009 May;18(5):560-3. doi: 10.1002/pon.1414.
Hunter MS, Mann E A cognitive model of menopausal hot flushes and night sweats. J Psychosom Res. 2010 Nov;69(5):491-501. doi: 10.1016/j.jpsychores.2010.04.005. Epub 2010 Jun 1.
Innes KE, Selfe TK, Vishnu A Mind-body therapies for menopausal symptoms: a systematic review. Maturitas. 2010 Jun;66(2):135-49. doi: 10.1016/j.maturitas.2010.01.016. Epub 2010 Feb 18. Review.
Lee MS, Shin BC, Ernst E Acupuncture for treating menopausal hot flushes: a systematic review. Climacteric. 2009 Feb;12(1):16-25. doi: 10.1080/13697130802566980. Review.
Nedstrand E, Wijma K, Wyon Y, Hammar M Applied relaxation and oral estradiol treatment of vasomotor symptoms in postmenopausal women. Maturitas. 2005 Jun 16;51(2):154-62.
Nedstrand E, Wijma K, Wyon Y, Hammar M Vasomotor symptoms decrease in women with breast cancer randomized to treatment with applied relaxation or electro-acupuncture: a preliminary study. Climacteric. 2005 Sep;8(3):243-50.
Wyon Y, Wijma K, Nedstrand E, Hammar M A comparison of acupuncture and oral estradiol treatment of vasomotor symptoms in postmenopausal women. Climacteric. 2004 Jun;7(2):153-64.
Applied Relaxation for Vasomotor Symptoms in Postmenopausal Women - a Randomized, Controlled Trial
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
