Meniscus Lesion — Platelet Rich Plasma Study With Meniscal Repair
Citation(s)
Andersson-Molina H, Karlsson H, Rockborn P Arthroscopic partial and total meniscectomy: A long-term follow-up study with matched controls. Arthroscopy. 2002 Feb;18(2):183-9.
Arnoczky SP, Warren RF The microvasculature of the meniscus and its response to injury. An experimental study in the dog. Am J Sports Med. 1983 May-Jun;11(3):131-41.
Cardello P, Gigli C, Ricci A, Chiatti L, Voglino N, Pofi E Retears of postoperative knee meniscus: findings on magnetic resonance imaging (MRI) and magnetic resonance arthrography (MRA) by using low and high field magnets. Skeletal Radiol. 2009 Feb;38(2)
Cox JS, Nye CE, Schaefer WW, Woodstein IJ The degenerative effects of partial and total resection of the medial meniscus in dogs' knees. Clin Orthop Relat Res. 1975;(109):178-83.
Elentuck D, Palmer WE Direct magnetic resonance arthrography. Eur Radiol. 2004 Nov;14(11):1956-67. Epub 2004 Sep 3. Review.
Eppley BL, Woodell JE, Higgins J Platelet quantification and growth factor analysis from platelet-rich plasma: implications for wound healing. Plast Reconstr Surg. 2004 Nov;114(6):1502-8.
FAIRBANK TJ Knee joint changes after meniscectomy. J Bone Joint Surg Br. 1948 Nov;30B(4):664-70.
Faunø P, Nielsen AB Arthroscopic partial meniscectomy: a long-term follow-up. Arthroscopy. 1992;8(3):345-9.
Fufa D, Shealy B, Jacobson M, Kevy S, Murray MM Activation of platelet-rich plasma using soluble type I collagen. J Oral Maxillofac Surg. 2008 Apr;66(4):684-90. doi: 10.1016/j.joms.2007.06.635.
Fukubayashi T, Kurosawa H The contact area and pressure distribution pattern of the knee. A study of normal and osteoarthrotic knee joints. Acta Orthop Scand. 1980 Dec;51(6):871-9.
Gopez AG, Kavanagh EC MR imaging of the postoperative meniscus: repair, resection, and replacement. Semin Musculoskelet Radiol. 2006 Sep;10(3):229-40. Review.
Hashimoto J, Kurosaka M, Yoshiya S, Hirohata K Meniscal repair using fibrin sealant and endothelial cell growth factor. An experimental study in dogs. Am J Sports Med. 1992 Sep-Oct;20(5):537-41.
Kettelkamp DB, Jacobs AW Tibiofemoral contact area--determination and implications. J Bone Joint Surg Am. 1972 Mar;54(2):349-56.
Kirkley A, Griffin S, Whelan D The development and validation of a quality of life-measurement tool for patients with meniscal pathology: the Western Ontario Meniscal Evaluation Tool (WOMET). Clin J Sport Med. 2007 Sep;17(5):349-56.
Lietman SA, Hobbs W, Inoue N, Reddi AH Effects of selected growth factors on porcine meniscus in chemically defined medium. Orthopedics. 2003 Aug;26(8):799-803.
Logan M, Watts M, Owen J, Myers P Meniscal repair in the elite athlete: results of 45 repairs with a minimum 5-year follow-up. Am J Sports Med. 2009 Jun;37(6):1131-4. doi: 10.1177/0363546508330138. Epub 2009 Mar 11.
McDermott ID, Amis AA The consequences of meniscectomy. J Bone Joint Surg Br. 2006 Dec;88(12):1549-56. Review.
Muellner T, Egkher A, Nikolic A, Funovics M, Metz V Open meniscal repair: clinical and magnetic resonance imaging findings after twelve years. Am J Sports Med. 1999 Jan-Feb;27(1):16-20. Erratum in: Am J Sports Med 1999 May-Jun;27(3):379.
Quinn SF, Brown TF Meniscal tears diagnosed with MR imaging versus arthroscopy: how reliable a standard is arthroscopy? Radiology. 1991 Dec;181(3):843-7.
Scordino LE, Deberardino TM Biologic enhancement of meniscus repair. Clin Sports Med. 2012 Jan;31(1):91-100. doi: 10.1016/j.csm.2011.09.001. Review.
Scott GA, Jolly BL, Henning CE Combined posterior incision and arthroscopic intra-articular repair of the meniscus. An examination of factors affecting healing. J Bone Joint Surg Am. 1986 Jul;68(6):847-61.
Sethi PM, Cooper A, Jokl P Technical tips in orthopaedics: meniscal repair with use of an in situ fibrin clot. Arthroscopy. 2003 May-Jun;19(5):E44.
Vives MJ, Homesley D, Ciccotti MG, Schweitzer ME Evaluation of recurring meniscal tears with gadolinium-enhanced magnetic resonance imaging: a randomized, prospective study. Am J Sports Med. 2003 Nov-Dec;31(6):868-73.
Voloshin AS, Wosk J Shock absorption of meniscectomized and painful knees: a comparative in vivo study. J Biomed Eng. 1983 Apr;5(2):157-61.
Walker PS, Erkman MJ The role of the menisci in force transmission across the knee. Clin Orthop Relat Res. 1975;(109):184-92.
White LM, Kramer J, Recht MP MR imaging evaluation of the postoperative knee: ligaments, menisci, and articular cartilage. Skeletal Radiol. 2005 Aug;34(8):431-52. Epub 2005 Jun 21. Review.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.