NCT04860726 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Freburger JK, Holmes GM, Agans RP, Jackman AM, Darter JD, Wallace AS, Castel LD, Kalsbeek WD, Carey TS
The rising prevalence of chronic low back pain. Arch Intern Med. 2009 Feb 9;169(3):251-8. doi: 10.1001/archinternmed.2008.543.
Heneweer H, Staes F, Aufdemkampe G, van Rijn M, Vanhees L
Physical activity and low back pain: a systematic review of recent literature. Eur Spine J. 2011 Jun;20(6):826-45. doi: 10.1007/s00586-010-1680-7. Epub 2011 Jan 9. Review.
Johannes CB, Le TK, Zhou X, Johnston JA, Dworkin RH
The prevalence of chronic pain in United States adults: results of an Internet-based survey. J Pain. 2010 Nov;11(11):1230-9. doi: 10.1016/j.jpain.2010.07.002. Epub 2010 Aug 25.
Liao ZT, Pan YF, Huang JL, Huang F, Chi WJ, Zhang KX, Lin ZM, Wu YQ, He WZ, Wu J, Xie XJ, Huang JX, Wei QJ, Li TW, Wu Z, Yu BY, Gu JR
An epidemiological survey of low back pain and axial spondyloarthritis in a Chinese Han population. Scand J Rheumatol. 2009 Nov-Dec;38(6):455-9. doi: 10.3109/03009740902978085.
Meucci RD, Fassa AG, Faria NM
Prevalence of chronic low back pain: systematic review. Rev Saude Publica. 2015;49. pii: S0034-89102015000100408. doi: 10.1590/S0034-8910.2015049005874. Epub 2015 Oct 20. Review.
Meucci RD, Fassa AG, Paniz VM, Silva MC, Wegman DH
Increase of chronic low back pain prevalence in a medium-sized city of southern Brazil. BMC Musculoskelet Disord. 2013 May 1;14:155. doi: 10.1186/1471-2474-14-155.
Olafsson G, Jonsson E, Fritzell P, Hägg O, Borgström F
Cost of low back pain: results from a national register study in Sweden. Eur Spine J. 2018 Nov;27(11):2875-2881. doi: 10.1007/s00586-018-5742-6. Epub 2018 Aug 28.

Effects of Myofascial Release and Joint Mobilization Therapy on Pain, Muscle Thickness, Range of Motion and Functional Disability in Non-Specific Low Back Pain

Details for clinical trial NCT04860726

Clinical trial NCT04860726 - References