NCT02774356 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Bidelman GM, Gandour JT, Krishnan A
Musicians and tone-language speakers share enhanced brainstem encoding but not perceptual benefits for musical pitch. Brain Cogn. 2011 Oct;77(1):1-10. doi: 10.1016/j.bandc.2011.07.006.
Krishnan A, Xu Y, Gandour J, Cariani P
Encoding of pitch in the human brainstem is sensitive to language experience. Brain Res Cogn Brain Res. 2005 Sep;25(1):161-8.
Marmel F, Linley D, Carlyon RP, Gockel HE, Hopkins K, Plack CJ
Subcortical neural synchrony and absolute thresholds predict frequency discrimination independently. J Assoc Res Otolaryngol. 2013 Oct;14(5):757-66. doi: 10.1007/s10162-013-0402-3.
Xu Q, Gong Q
Frequency difference beyond behavioral limen reflected by frequency following response of human auditory Brainstem. Biomed Eng Online. 2014 Aug 9;13:114. doi: 10.1186/1475-925X-13-114.
Zhang Y, Kuhl PK, Imada T, Kotani M, Tohkura Y
Effects of language experience: neural commitment to language-specific auditory patterns. Neuroimage. 2005 Jul 1;26(3):703-20.

Testing Native Language Neural Commitment at the Subcortical Level: Links Between Brainstem Frequency Following Responses and Behavioral Perception for Lexical Tones

Details for clinical trial NCT02774356

Clinical trial NCT02774356 - References