Clinical trial NCT05668468 - References

Lactose Intolerance — A Bifido Bacteria to Improve Lactose Digestion and Tolerance

Citation(s)

•   Brandao Gois MF, Sinha T, Spreckels JE, Vich Vila A, Bolte LA, Weersma RK, Wijmenga C, Fu J, Zhernakova A, Kurilshikov A
  Role of the gut microbiome in mediating lactose intolerance symptoms. Gut. 2022 Jan;71(1):215-217. doi: 10.1136/gutjnl-2020-323911. Epub 2021 Mar 18. No abstract available.
•   Davis LM, Martinez I, Walter J, Hutkins R
  A dose dependent impact of prebiotic galactooligosaccharides on the intestinal microbiota of healthy adults. Int J Food Microbiol. 2010 Dec 15;144(2):285-92. doi: 10.1016/j.ijfoodmicro.2010.10.007. Epub 2010 Oct 14.
•   Fuller R, Gibson GR
  Modification of the intestinal microflora using probiotics and prebiotics. Scand J Gastroenterol Suppl. 1997;222:28-31. doi: 10.1080/00365521.1997.11720714.
•   He T, Roelofsen H, Alvarez-Llamas G, de Vries M, Venema K, Welling GW, Vonk RJ
  Differential analysis of protein expression of Bifidobacterium grown on different carbohydrates. J Microbiol Methods. 2007 May;69(2):364-70. doi: 10.1016/j.mimet.2007.02.008. Epub 2007 Feb 28.
•   Hertzler SR, Savaiano DA, Levitt MD
  Fecal hydrogen production and consumption measurements. Response to daily lactose ingestion by lactose maldigesters. Dig Dis Sci. 1997 Feb;42(2):348-53. doi: 10.1023/a:1018822103911.
•   Hertzler SR, Savaiano DA
  Colonic adaptation to daily lactose feeding in lactose maldigesters reduces lactose intolerance. Am J Clin Nutr. 1996 Aug;64(2):232-6. doi: 10.1093/ajcn/64.2.232.
•   Jiang T, Mustapha A, Savaiano DA
  Improvement of lactose digestion in humans by ingestion of unfermented milk containing Bifidobacterium longum. J Dairy Sci. 1996 May;79(5):750-7. doi: 10.3168/jds.S0022-0302(96)76422-6.
•   Kocian J
  Further possibilities in the treatment of lactose intolerance--lactobacilli. Prakticky Lekar. 1994; 74: 212-214.
•   Krumbeck JA, Maldonado-Gomez MX, Martinez I, Frese SA, Burkey TE, Rasineni K, Ramer-Tait AE, Harris EN, Hutkins RW, Walter J
  In vivo selection to identify bacterial strains with enhanced ecological performance in synbiotic applications. Appl Environ Microbiol. 2015 Apr;81(7):2455-65. doi: 10.1128/AEM.03903-14. Epub 2015 Jan 23.
•   Leis R, de Castro MJ, de Lamas C, Picans R, Couce ML
  Effects of Prebiotic and Probiotic Supplementation on Lactase Deficiency and Lactose Intolerance: A Systematic Review of Controlled Trials. Nutrients. 2020 May 20;12(5):1487. doi: 10.3390/nu12051487.
•   O'Sullivan MG, Thornton G, O'Sullivan GC, Collins JK
  Probiotic bacteria: myth or realilty. Trends in Food Science & Technology. 2010; 3: 309-314
•   Reid G
  Safety of lactobacillus strains as probiotic agents. Clin Infect Dis. 2002 Aug 1;35(3):349-50. doi: 10.1086/342477. No abstract available.
•   Sharma M, Wasan A, Sharma RK
  Recent developments in probiotics: An emphasis on bifidobacterium. Food Bioscience. 2021;41: 100993.
•   Vitellio P, Celano G, Bonfrate L, Gobbetti M, Portincasa P, De Angelis M
  Effects of Bifidobacterium longum and Lactobacillus rhamnosus on Gut Microbiota in Patients with Lactose Intolerance and Persisting Functional Gastrointestinal Symptoms: A Randomised, Double-Blind, Cross-Over Study. Nutrients. 2019 Apr 19;11(4):886. doi: 10.3390/nu11040886.

Can Feeding a Bifido Bacteria That Readily Digests Lactose and Galactooligosacharides Improve Lactose Digestion and Tolerance Through Alteration of the Microbiome?

Details for clinical trial NCT05668468