NCT05338840 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Epskamp S, Dibley H, Ray E, Bond N, White J, Wilkinson A, et al
Range of motion as an outcome measure for knee osteoarthritis interventions in clinical trials: an integrated review. Physical Therapy Reviews. 2020;25(5-6):462-81.
Lalnunpuii A, Sarkar B, Alam S, Equebal A, Biswas A
Efficacy of mulligan mobilisation as compared to Maitland mobilisation in females with knee osteoarthritis: a double blind randomized controlled trial. International Journal of Therapies and Rehabilitation Research. 2017;6(2):37.
Lespasio MJ, Piuzzi NS, Husni ME, Muschler GF, Guarino A, Mont MA
Knee Osteoarthritis: A Primer. Perm J. 2017;21:16-183. doi: 10.7812/TPP/16-183.
Mehmood Z, Anwar N, Tauqeer S, Shabbir M, Khalid K, Mehmood S
Comparison of Maitland Mobilization and Mulligan Mobilization with Movement in Knee Osteoarthritis Patients. Pakistan Journal of Medical Research. 2021;60(3):126-30
Rao RV, Balthillaya G, Prabhu A, Kamath A
Immediate effects of Maitland mobilization versus Mulligan Mobilization with Movement in Osteoarthritis knee- A Randomized Crossover trial. J Bodyw Mov Ther. 2018 Jul;22(3):572-579. doi: 10.1016/j.jbmt.2017.09.017. Epub 2017 Sep 28.
SNB N, Ali S, Akhtar S
Effectiveness of Mulligan Joint Mobilizations and Trunk Stabilization Exercises Versus Isometric Knee Strengthening in the Management of Knee Osteoarthritis: Study Protocol for a Randomized Controlled Trial. 2020

Effects of Mulligan Rotational Movement Versus Medial Gapping Technique on Pain, Range of Motion and Disability in Patients With Knee Osteoarthritis

Clinical trial NCT05338840 - References