NCT04307160 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Abroms AD, Mohney BG, Rush DP, Parks MM, Tong PY
Timely surgery in intermittent and constant exotropia for superior sensory outcome. Am J Ophthalmol. 2001 Jan;131(1):111-6.
Buck D, Powell CJ, Sloper JJ, Taylor R, Tiffin P, Clarke MP; Improving Outcomes in Intermittent Exotropia (IOXT) Study group
Surgical intervention in childhood intermittent exotropia: current practice and clinical outcomes from an observational cohort study. Br J Ophthalmol. 2012 Oct;96(10):1291-5. Epub 2012 Aug 11.
Choi J, Kim SJ, Yu YS
Initial postoperative deviation as a predictor of long-term outcome after surgery for intermittent exotropia. J AAPOS. 2011 Jun;15(3):224-9. doi: 10.1016/j.jaapos.2010.12.019. Epub 2011 Jun 12.
Haggerty H, Richardson S, Hrisos S, Strong NP, Clarke MP
The Newcastle Control Score: a new method of grading the severity of intermittent distance exotropia. Br J Ophthalmol. 2004 Feb;88(2):233-5.
Pratt-Johnson JA, Barlow JM, Tillson G
Early surgery in intermittent exotropia. Am J Ophthalmol. 1977 Nov;84(5):689-94.
Richard JM, Parks MM
Intermittent exotropia. Surgical results in different age groups. Ophthalmology. 1983 Oct;90(10):1172-7.

Effect of Age at Time of Surgery on the Surgical Outcome After Bilateral Lateral Rectus Muscle Recession in Intermittent Exotropia

Clinical trial NCT04307160 - References