Intensive Care — Drug Administration From Enteral Nutrition Tube
Citation(s)
Abu Hdaib N, Albsoul-Younes A, Wazaify M Oral medications administration through enteral feeding tube: Clinical pharmacist-led educational intervention to improve knowledge of Intensive care units' nurses at Jordan University Hospital. Saudi Pharm J. 2021 Feb;29(2):134-142. doi: 10.1016/j.jsps.2020.12.015. Epub 2021 Jan 7.
Demirkan K, Ekincioglu AB Enteral Beslenme Tüpünden Ilaç Uygulanmasinda Ilaç Dozaj Sekillerinin Önemi. Journal of the Turkish Society of Intensive Care/Türk Yogun Bakim Dernegi Dergisi. 2016;14(1):1-8.
Ekincioglu AB, Demirkan K Clinical nutrition and drug interactions. Ulus Cerrahi Derg. 2013 Nov 14;29(4):177-86. doi: 10.5152/UCD.2013.112013. eCollection 2013.
Özkan D, Yavuz Van Giersbergen M Güvenli Cerrahi Kontrol Listesi Konusunda Ameliyathane Ekibinin Düsüncelerinin Incelenmesi. Turkiye Klinikleri J Surg Nurs-Special Topics Türkiye Klinikleri Cerrahi Hastaliklari Hemsireligi-Güvenli Cerrahi Uygulamalari Özel Sayisi. 2016;2(3):22-8
Sari D, Kadifeli D, Akbiyik A, Taskiran N Intensive care unit nurses' knowledge of medication administration via enteral tubes. Nurs Crit Care. 2018 May;23(3):141-146. doi: 10.1111/nicc.12335. Epub 2018 Feb 8.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
