Insulin Resistance — The Influence of Daily Honey Consumption on IR in Obese Women With IR
Citation(s)
Abbey EL, Rankin JW Effect of ingesting a honey-sweetened beverage on soccer performance and exercise-induced cytokine response. Int J Sport Nutr Exerc Metab. 2009 Dec;19(6):659-72. doi: 10.1123/ijsnem.19.6.659.
Abu Rajab, A , Takruri, H., Mishal, A., & Alkurd, R. Glycemic and Insulinemic Response of Different Types of Jordanian Honey in Healthy and Type 2 Diabetic Volunteers. Pakistan Journal of Nutrition, 2017; 16(2), 61-68.
Ajibola A , Physico-Chemical and Physiological Values of Honey and Its Importance as a Functional Food, International Journal of Food Sciences and Nutrition, 2015;2(6):1-9.
Al-Ismail K , Herzallah, S. M., &Rustom, A. S. Antioxidant activities of some edible wild mediterranean plants. Italian Journal of Food Science, 2007; 19(3).
Al-Waili NS Natural honey lowers plasma glucose, C-reactive protein, homocysteine, and blood lipids in healthy, diabetic, and hyperlipidemic subjects: comparison with dextrose and sucrose. J Med Food. 2004 Spring;7(1):100-7. doi: 10.1089/1096620043229847
Alvarez-Suarez J M. , Tulipani S., Romandini S., Bertoli E., and Battino M., Contribution of honey in nutrition and human health: a review, Mediterranean Journal of Nutrition and Metabolism, 2010;3(1):15-23.
Ferreres F , García-Viguera C., Tomás-Lorente F., and Tomás-Barberán F.A., Hesperetin: a marker of the floral origin of citrus honey, Journal of the Science of Food and Agriculture, vol. 61, no. 1, pp. 121-123, 1993.
Giugliano D, Ceriello A, Paolisso G Oxidative stress and diabetic vascular complications. Diabetes Care. 1996 Mar;19(3):257-67. doi: 10.2337/diacare.19.3.257.
Kumar S , Safi S. Z., Qvist R., and Ismail I. S., Effect of agonists of adenosine receptors on inflammatory markers in human Muller cells, Current Science, 2014;106(4):582-586.
Li N, Brun T, Cnop M, Cunha DA, Eizirik DL, Maechler P Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction. J Biol Chem. 2009 Aug 28;284(35):23602-12. doi: 10.1074/jbc.M109.024323. Epub 2009 Jun 22.
Molan PC A brief review of honey as a clinical dressing. Prim Intention. 1998;6:148-158.
Moniruzzaman M, Khalil MI, Sulaiman SA, Gan SH Advances in the analytical methods for determining the antioxidant properties of honey: a review. Afr J Tradit Complement Altern Med. 2011 Oct 2;9(1):36-42. doi: 10.4314/ajtcam.v9i1.5. eCollection 2012.
Pasupuleti VR, Sammugam L, Ramesh N, Gan SH Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits. Oxid Med Cell Longev. 2017;2017:1259510. doi: 10.1155/2017/1259510. Epub 2017 Jul 26.
Qi Q, Bray GA, Smith SR, Hu FB, Sacks FM, Qi L Insulin receptor substrate 1 gene variation modifies insulin resistance response to weight-loss diets in a 2-year randomized trial: the Preventing Overweight Using Novel Dietary Strategies (POUNDS LOST) tria
Rao P V., Krishnan K.T., Salleh N., and Gan S.H., Biological and therapeutic effects of honey produced by honey bees and stingless bees: a comparative review, RevistaBrasileira de Farmacognosia. 2016;26(5):657-664.
Riccardi G, Giacco R, Rivellese AA Dietary fat, insulin sensitivity and the metabolic syndrome. Clin Nutr. 2004 Aug;23(4):447-56. doi: 10.1016/j.clnu.2004.02.006.
Safi SZ, Qvist R, Yan GO, Ismail IS Differential expression and role of hyperglycemia induced oxidative stress in epigenetic regulation of beta1, beta2 and beta3-adrenergic receptors in retinal endothelial cells. BMC Med Genomics. 2014 May 30;7:29. doi:
Samuel VT, Shulman GI Mechanisms for insulin resistance: common threads and missing links. Cell. 2012 Mar 2;148(5):852-71. doi: 10.1016/j.cell.2012.02.017.
Sattar N , Perry C.G., and Petrie J. R. Type 2 diabetes as an inflammatory disorder, The British Journal of Diabetes and Vascular Disease, 2003;3(1):36-41.
Tartibian B, Maleki BH The effects of honey supplementation on seminal plasma cytokines, oxidative stress biomarkers, and antioxidants during 8 weeks of intensive cycling training. J Androl. 2012 May-Jun;33(3):449-61. doi: 10.2164/jandrol.110.012815. Epu
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.