Braun JM, Gennings C, Hauser R, Webster TF What Can Epidemiological Studies Tell Us about the Impact of Chemical Mixtures on Human Health? Environ Health Perspect. 2016 Jan;124(1):A6-9. doi: 10.1289/ehp.1510569.
Braun JM, Just AC, Williams PL, Smith KW, Calafat AM, Hauser R Personal care product use and urinary phthalate metabolite and paraben concentrations during pregnancy among women from a fertility clinic. J Expo Sci Environ Epidemiol. 2014 Sep-Oct;24(5):45
Braun JM, Sathyanarayana S, Hauser R Phthalate exposure and children's health. Curr Opin Pediatr. 2013 Apr;25(2):247-54. doi: 10.1097/MOP.0b013e32835e1eb6. Review.
Chavarro JE, Toth TL, Sadio SM, Hauser R Soy food and isoflavone intake in relation to semen quality parameters among men from an infertility clinic. Hum Reprod. 2008 Nov;23(11):2584-90. doi: 10.1093/humrep/den243. Epub 2008 Jul 23.
Chavarro JE, Toth TL, Wright DL, Meeker JD, Hauser R Body mass index in relation to semen quality, sperm DNA integrity, and serum reproductive hormone levels among men attending an infertility clinic. Fertil Steril. 2010 May 1;93(7):2222-31. doi: 10.1016
Chen Z, Godfrey-Bailey L, Schiff I, Hauser R Impact of seasonal variation, age and smoking status on human semen parameters: The Massachusetts General Hospital experience. J Exp Clin Assist Reprod. 2004 Sep 30;1(1):2.
Duty SM, Ackerman RM, Calafat AM, Hauser R Personal care product use predicts urinary concentrations of some phthalate monoesters. Environ Health Perspect. 2005 Nov;113(11):1530-5.
Hu Y, Chiu YH, Hauser R, Chavarro J, Sun Q Overall and class-specific scores of pesticide residues from fruits and vegetables as a tool to rank intake of pesticide residues in United States: A validation study. Environ Int. 2016 Jul-Aug;92-93:294-300. do
Johnson PI, Stapleton HM, Mukherjee B, Hauser R, Meeker JD Associations between brominated flame retardants in house dust and hormone levels in men. Sci Total Environ. 2013 Feb 15;445-446:177-84. doi: 10.1016/j.scitotenv.2012.12.017. Epub 2013 Jan 16.
Johnson PI, Stapleton HM, Sjodin A, Meeker JD Relationships between polybrominated diphenyl ether concentrations in house dust and serum. Environ Sci Technol. 2010 Jul 15;44(14):5627-32. doi: 10.1021/es100697q.
Lewis RC, Hauser R, Wang L, Kavet R, Meeker JD Personal power-frequency magnetic field exposure in women recruited at an infertility clinic: association with physical activity and temporal variability. Radiat Prot Dosimetry. 2016 Mar;168(4):478-88. doi:
McAuliffe ME, Williams PL, Korrick SA, Altshul LM, Perry MJ Environmental exposure to polychlorinated biphenyls and p,p'-DDE and sperm sex-chromosome disomy. Environ Health Perspect. 2012 Apr;120(4):535-40. doi: 10.1289/ehp.1104017. Epub 2011 Dec 21.
McAuliffe ME, Williams PL, Korrick SA, Dadd R, Perry MJ The association between sperm sex chromosome disomy and semen concentration, motility and morphology. Hum Reprod. 2012 Oct;27(10):2918-26. doi: 10.1093/humrep/des302. Epub 2012 Aug 14.
Meeker JD, Altshul L, Hauser R Serum PCBs, p,p'-DDE and HCB predict thyroid hormone levels in men. Environ Res. 2007 Jun;104(2):296-304. Epub 2006 Dec 26.
Meeker JD, Barr DB, Hauser R Pyrethroid insecticide metabolites are associated with serum hormone levels in adult men. Reprod Toxicol. 2009 Apr;27(2):155-60. doi: 10.1016/j.reprotox.2008.12.012. Epub 2009 Jan 24.
Meeker JD, Calafat AM, Hauser R Di(2-ethylhexyl) phthalate metabolites may alter thyroid hormone levels in men. Environ Health Perspect. 2007 Jul;115(7):1029-34.
Meeker JD, Calafat AM, Hauser R Urinary bisphenol A concentrations in relation to serum thyroid and reproductive hormone levels in men from an infertility clinic. Environ Sci Technol. 2010 Feb 15;44(4):1458-63. doi: 10.1021/es9028292.
Meeker JD, Calafat AM, Hauser R Urinary metabolites of di(2-ethylhexyl) phthalate are associated with decreased steroid hormone levels in adult men. J Androl. 2009 May-Jun;30(3):287-97. doi: 10.2164/jandrol.108.006403. Epub 2008 Dec 4.
Meeker JD, Calafat AM, Hauser R Urinary phthalate metabolites and their biotransformation products: predictors and temporal variability among men and women. J Expo Sci Environ Epidemiol. 2012 Jul;22(4):376-85. doi: 10.1038/jes.2012.7. Epub 2012 Feb 22.
Meeker JD, Cooper EM, Stapleton HM, Hauser R Exploratory analysis of urinary metabolites of phosphorus-containing flame retardants in relation to markers of male reproductive health. Endocr Disruptors (Austin). 2013 Oct 1;1(1):e26306.
Meeker JD, Cooper EM, Stapleton HM, Hauser R Urinary metabolites of organophosphate flame retardants: temporal variability and correlations with house dust concentrations. Environ Health Perspect. 2013 May;121(5):580-5. doi: 10.1289/ehp.1205907. Epub 201
Meeker JD, Johnson PI, Camann D, Hauser R Polybrominated diphenyl ether (PBDE) concentrations in house dust are related to hormone levels in men. Sci Total Environ. 2009 May 1;407(10):3425-9. doi: 10.1016/j.scitotenv.2009.01.030. Epub 2009 Feb 10.
Meeker JD, Ravi SR, Barr DB, Hauser R Circulating estradiol in men is inversely related to urinary metabolites of nonpersistent insecticides. Reprod Toxicol. 2008 Feb;25(2):184-91. doi: 10.1016/j.reprotox.2007.12.005. Epub 2007 Dec 28.
Meeker JD, Singh NP, Hauser R Serum concentrations of estradiol and free T4 are inversely correlated with sperm DNA damage in men from an infertility clinic. J Androl. 2008 Jul-Aug;29(4):379-88. doi: 10.2164/jandrol.107.004416. Epub 2008 Mar 20.
Meeker JD, Stapleton HM House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parameters. Environ Health Perspect. 2010 Mar;118(3):318-23. doi: 10.1289/ehp.0901332.
Meeker JD, Yang T, Ye X, Calafat AM, Hauser R Urinary concentrations of parabens and serum hormone levels, semen quality parameters, and sperm DNA damage. Environ Health Perspect. 2011 Feb;119(2):252-7. doi: 10.1289/ehp.1002238. Epub 2010 Sep 28.
Mínguez-Alarcón L, Hauser R, Gaskins AJ Effects of bisphenol A on male and couple reproductive health: a review. Fertil Steril. 2016 Sep 15;106(4):864-70. doi: 10.1016/j.fertnstert.2016.07.1118. Epub 2016 Aug 4. Review.
Perry MJ, Chen X, McAuliffe ME, Maity A, Deloid GM Semi-automated scoring of triple-probe FISH in human sperm: methods and further validation. Cytometry A. 2011 Aug;79(8):661-6. doi: 10.1002/cyto.a.21078. Epub 2011 May 12.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.