NCT05762770 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Hodes-Wertz B, Grifo J, Ghadir S, Kaplan B, Laskin CA, Glassner M, Munne S
Idiopathic recurrent miscarriage is caused mostly by aneuploid embryos. Fertil Steril. 2012 Sep;98(3):675-80. doi: 10.1016/j.fertnstert.2012.05.025. Epub 2012 Jun 7.
Lepine S, McDowell S, Searle LM, Kroon B, Glujovsky D, Yazdani A
Advanced sperm selection techniques for assisted reproduction. Cochrane Database Syst Rev. 2019 Jul 30;7(7):CD010461. doi: 10.1002/14651858.CD010461.pub3.
McDowell S, Kroon B, Ford E, Hook Y, Glujovsky D, Yazdani A
Advanced sperm selection techniques for assisted reproduction. Cochrane Database Syst Rev. 2014 Oct 28;(10):CD010461. doi: 10.1002/14651858.CD010461.pub2.

A Randomised Controlled Trial to Explore the Effect of Physiological Intracytoplasmic Sperm Injection (PICSI) on Miscarriage Rates in Assisted Conception

Details for clinical trial NCT05762770

Clinical trial NCT05762770 - References