Clinical trial NCT03483298 - References

Infertility — Split Cohort Trial Comparing IVF Outcomes After the Use of Testicular vs. Ejaculated Sperm for ICSI

Citation(s)

•   Bradley CK, McArthur SJ, Gee AJ, Weiss KA, Schmidt U, Toogood L
  Intervention improves assisted conception intracytoplasmic sperm injection outcomes for patients with high levels of sperm DNA fragmentation: a retrospective analysis. Andrology. 2016 Sep;4(5):903-10. doi: 10.1111/andr.12215. Epub 2016 May 27.
•   Esteves SC, Sánchez-Martín F, Sánchez-Martín P, Schneider DT, Gosálvez J
  Comparison of reproductive outcome in oligozoospermic men with high sperm DNA fragmentation undergoing intracytoplasmic sperm injection with ejaculated and testicular sperm. Fertil Steril. 2015 Dec;104(6):1398-405. doi: 10.1016/j.fertnstert.2015.08.028. Epub 2015 Oct 1.
•   Greco E, Scarselli F, Iacobelli M, Rienzi L, Ubaldi F, Ferrero S, Franco G, Anniballo N, Mendoza C, Tesarik J
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•   Lewis SE, John Aitken R, Conner SJ, Iuliis GD, Evenson DP, Henkel R, Giwercman A, Gharagozloo P
  The impact of sperm DNA damage in assisted conception and beyond: recent advances in diagnosis and treatment. Reprod Biomed Online. 2013 Oct;27(4):325-37. doi: 10.1016/j.rbmo.2013.06.014. Epub 2013 Jul 11. Review.
•   Mehta A, Bolyakov A, Schlegel PN, Paduch DA
  Higher pregnancy rates using testicular sperm in men with severe oligospermia. Fertil Steril. 2015 Dec;104(6):1382-7. doi: 10.1016/j.fertnstert.2015.08.008. Epub 2015 Sep 9.
•   Pabuccu EG, Caglar GS, Tangal S, Haliloglu AH, Pabuccu R
  Testicular versus ejaculated spermatozoa in ICSI cycles of normozoospermic men with high sperm DNA fragmentation and previous ART failures. Andrologia. 2017 Mar;49(2). doi: 10.1111/and.12609. Epub 2016 Apr 25.

Prospective Split Cohort Trial Comparing in Vitro Fertilization (IVF) Outcomes After the Use of Testicular Versus Ejaculated Sperm for ICSI in Med With Elevated DNA Fragmentation After a Failed IVF Cycle

Details for clinical trial NCT03483298