Hypothermia — Amino Acid Infusion in Mothers Before and During Cesarean Delivery
Citation(s)
Brundin T, Wahren J Effects of i.v. amino acids on human splanchnic and whole body oxygen consumption, blood flow, and blood temperatures. Am J Physiol. 1994 Mar;266(3 Pt 1):E396-402.
Brundin T, Wahren J Influence of protein ingestion on human splanchnic and whole-body oxygen consumption, blood flow, and blood temperature. Metabolism. 1994 May;43(5):626-32.
Fallis WM, Hamelin K, Symonds J, Wang X Maternal and newborn outcomes related to maternal warming during cesarean delivery. J Obstet Gynecol Neonatal Nurs. 2006 May-Jun;35(3):324-31.
Heier T, Caldwell JE, Sessler DI, Miller RD Mild intraoperative hypothermia increases duration of action and spontaneous recovery of vecuronium blockade during nitrous oxide-isoflurane anesthesia in humans. Anesthesiology. 1991 May;74(5):815-9.
Jequier E The influence of nutrient administration on energy expenditure in man. Clin Nutr. 1986 Nov;5(4):181-6.
Kurz A, Sessler DI, Lenhardt R Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. Study of Wound Infection and Temperature Group. N Engl J Med. 1996 May 9;334(19):1209-15.
Saitoh Y, Kaneda K, Tokunaga Y, Murakawa M Infusion of amino acid enriched solution hastens recovery from neuromuscular block caused by vecuronium. Br J Anaesth. 2001 Jun;86(6):814-21. Retraction in: Br J Anaesth. 2019 Jan;122(1):155.
Selldén E, Bränström R, Brundin T Preoperative infusion of amino acids prevents postoperative hypothermia. Br J Anaesth. 1996 Feb;76(2):227-34.
Selldén E, Brundin T, Wahren J Augmented thermic effect of amino acids under general anaesthesia: a mechanism useful for prevention of anaesthesia-induced hypothermia. Clin Sci (Lond). 1994 May;86(5):611-8.
Selldén E, Lindahl SG Amino acid-induced thermogenesis reduces hypothermia during anesthesia and shortens hospital stay. Anesth Analg. 1999 Dec;89(6):1551-6.
Sessler DI, Rubinstein EH, Moayeri A Physiologic responses to mild perianesthetic hypothermia in humans. Anesthesiology. 1991 Oct;75(4):594-610.
Sessler DI Mild perioperative hypothermia. N Engl J Med. 1997 Jun 12;336(24):1730-7. Review.
Wang C, Han LY, Zhang LJ, Wang DH [Effect of aggressive nutritional support on preterm infants during hospitalization]. Zhonghua Er Ke Za Zhi. 2011 Oct;49(10):771-5. Chinese.
Widman J, Hammarqvist F, Selldén E Amino acid infusion induces thermogenesis and reduces blood loss during hip arthroplasty under spinal anesthesia. Anesth Analg. 2002 Dec;95(6):1757-62, table of contents.
Xing A, Wan B, Zeng W [Biochemical effects of maternal intravenous and intra-amniotic infusion of amino-acids on fetal blood]. Hua Xi Yi Ke Da Xue Xue Bao. 1994 Mar;25(1):98-102. Chinese.
Intravenous Amino Acid Infusion in Mothers Before and During Cesarean Delivery: Effects on Maternal and Neonatal Temperature
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.