NCT04682717 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Jain U, Laflamme CJ, Aggarwal A, Ramsay JG, Comunale ME, Ghoshal S, Ngo L, Ziola K, Hollenberg M, Mangano DT
Electrocardiographic and hemodynamic changes and their association with myocardial infarction during coronary artery bypass surgery. A multicenter study. Multicenter Study of Perioperative Ischemia (McSPI) Research Group. Anesthesiology. 1997 Mar;86(3):576-91.
Loeb RG
A measure of intraoperative attention to monitor displays. Anesth Analg. 1993 Feb;76(2):337-41.
Reich DL, Hossain S, Krol M, Baez B, Patel P, Bernstein A, Bodian CA
Predictors of hypotension after induction of general anesthesia. Anesth Analg. 2005 Sep;101(3):622-8, table of contents.
van Genderen ME, Bartels SA, Lima A, Bezemer R, Ince C, Bakker J, van Bommel J
Peripheral perfusion index as an early predictor for central hypovolemia in awake healthy volunteers. Anesth Analg. 2013 Feb;116(2):351-6. doi: 10.1213/ANE.0b013e318274e151. Epub 2013 Jan 9.

Perfusion Index as a Predictor of Hypotension Following Propofol Induction of General Anesthesia in Geriatric Patients - A Prospective Observational Study.

Details for clinical trial NCT04682717

Clinical trial NCT04682717 - References