NCT03091140 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Almqvist EG, Bondeson AG, Bondeson L, Svensson J
Increased markers of inflammation and endothelial dysfunction in patients with mild primary hyperparathyroidism. Scand J Clin Lab Invest. 2011 Apr;71(2):139-44. doi: 10.3109/00365513.2010.543694. Epub 2010 Dec 20.
Cheng SP, Liu CL, Liu TP, Hsu YC, Lee JJ
Association between parathyroid hormone levels and inflammatory markers among US adults. Mediators Inflamm. 2014;2014:709024. doi: 10.1155/2014/709024. Epub 2014 Mar 23.
Emam AA, Mousa SG, Ahmed KY, Al-Azab AA
Inflammatory biomarkers in patients with asymptomatic primary hyperparathyroidism. Med Princ Pract. 2012;21(3):249-53. doi: 10.1159/000334588. Epub 2011 Dec 16.
Farahnak P, Ring M, Caidahl K, Farnebo LO, Eriksson MJ, Nilsson IL
Cardiac function in mild primary hyperparathyroidism and the outcome after parathyroidectomy. Eur J Endocrinol. 2010 Sep;163(3):461-7. doi: 10.1530/EJE-10-0201. Epub 2010 Jun 18.
Piovesan A, Molineri N, Casasso F, Emmolo I, Ugliengo G, Cesario F, Borretta G
Left ventricular hypertrophy in primary hyperparathyroidism. Effects of successful parathyroidectomy. Clin Endocrinol (Oxf). 1999 Mar;50(3):321-8.
Rolighed L, Amstrup AK, Jakobsen NF, Sikjaer T, Mosekilde L, Christiansen P, Rejnmark L
Muscle function is impaired in patients with "asymptomatic" primary hyperparathyroidism. World J Surg. 2014 Mar;38(3):549-57. doi: 10.1007/s00268-013-2273-5.
Walker MD, Rundek T, Homma S, DiTullio M, Iwata S, Lee JA, Choi J, Liu R, Zhang C, McMahon DJ, Sacco RL, Silverberg SJ
Effect of parathyroidectomy on subclinical cardiovascular disease in mild primary hyperparathyroidism. Eur J Endocrinol. 2012 Aug;167(2):277-85. doi: 10.1530/EJE-12-0124. Epub 2012 Jun 1.

Alterations in Muscle's Functional Characteristics After Parathyroid Surgery for Primary Hyperparathyroidism.

Details for clinical trial NCT03091140

Clinical trial NCT03091140 - References