HIV Prevention Program — Testing of the JomPrEP App for HIV Prevention Among Malaysian MSM
Citation(s)
Biello KB, Marrow E, Mimiaga MJ, Sullivan P, Hightow-Weidman L, Mayer KH A Mobile-Based App (MyChoices) to Increase Uptake of HIV Testing and Pre-Exposure Prophylaxis by Young Men Who Have Sex With Men: Protocol for a Pilot Randomized Controlled Trial. JMIR Res Protoc. 2019 Jan 7;8(1):e10694. doi: 10.2196/10694.
Chawarski MC, Vicknasingam B, Mazlan M, Schottenfeld RS Lifetime ATS use and increased HIV risk among not-in-treatment opiate injectors in Malaysia. Drug Alcohol Depend. 2012 Jul 1;124(1-2):177-80. doi: 10.1016/j.drugalcdep.2011.12.024. Epub 2012 Jan 21.
Conserve DF, Jennings L, Aguiar C, Shin G, Handler L, Maman S Systematic review of mobile health behavioural interventions to improve uptake of HIV testing for vulnerable and key populations. J Telemed Telecare. 2017 Feb;23(2):347-359. doi: 10.1177/1357633X16639186. Epub 2016 Jul 9.
Cooper V, Clatworthy J, Whetham J, Consortium E mHealth Interventions To Support Self-Management In HIV: A Systematic Review. Open AIDS J. 2017 Nov 21;11:119-132. doi: 10.2174/1874613601711010119. eCollection 2017.
Fendrich M, Avci O, Johnson TP, Mackesy-Amiti ME Depression, substance use and HIV risk in a probability sample of men who have sex with men. Addict Behav. 2013 Mar;38(3):1715-8. doi: 10.1016/j.addbeh.2012.09.005. Epub 2012 Sep 24.
Halkitis PN, Parsons JT Recreational Drug Use and HIV-Risk Sexual Behavior Among Men Frequenting Gay Social Venues. Journal of Gay & Lesbian Social Services. 2002;14(4):19-38.
Mbuagbaw L, Mursleen S, Lytvyn L, Smieja M, Dolovich L, Thabane L Mobile phone text messaging interventions for HIV and other chronic diseases: an overview of systematic reviews and framework for evidence transfer. BMC Health Serv Res. 2015 Jan 22;15:33. doi: 10.1186/s12913-014-0654-6.
Milward J, Lynskey M, Strang J Solving the problem of non-attendance in substance abuse services. Drug Alcohol Rev. 2014 Nov;33(6):625-36. doi: 10.1111/dar.12194. Epub 2014 Sep 6.
Sharpe JD, Kamara MT A systematic evaluation of mobile apps to improve the uptake of and adherence to HIV pre-exposure prophylaxis. Sex Health. 2018 Nov;15(6):587-594. doi: 10.1071/SH18120.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
