NCT02471313 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Durand RE, Aquino-Parsons C
Non-constant tumour blood flow--implications for therapy. Acta Oncol. 2001;40(7):862-9.
THOMLINSON RH, GRAY LH
The histological structure of some human lung cancers and the possible implications for radiotherapy. Br J Cancer. 1955 Dec;9(4):539-49.
Vaupel P, Mayer A, Höckel M
Tumor hypoxia and malignant progression. Methods Enzymol. 2004;381:335-54.

A Pilot Study of an Integrated Imaging Strategy to Phenotype Progression of Liver Tumors During and After Chemoembolization

Clinical trial NCT02471313 - References