Hemianopsia — Therapeutic Effects of Transcranial Alternative Current Stimulation (tACS) in Chronic Post Stroke Hemianopia
Citation(s)
Alekseichuk I, Diers K, Paulus W, Antal A Transcranial electrical stimulation of the occipital cortex during visual perception modifies the magnitude of BOLD activity: A combined tES-fMRI approach. Neuroimage. 2016 Oct 15;140:110-7. doi: 10.1016/j.neuroimage.2015.11.034. Epub 2015 Nov 23.
Sahraie A Induced visual sensitivity changes in chronic hemianopia. Curr Opin Neurol. 2007 Dec;20(6):661-6. doi: 10.1097/WCO.0b013e3282f1c70f.
Schuett S, Dauner R, Zihl J Line bisection in unilateral homonymous visual field defects. Cortex. 2011 Jan;47(1):47-52. doi: 10.1016/j.cortex.2010.01.008. Epub 2010 Jan 28.
Sergeeva EG, Henrich-Noack P, Bola M, Sabel BA Brain-state-dependent non-invasive brain stimulation and functional priming: a hypothesis. Front Hum Neurosci. 2014 Nov 5;8:899. doi: 10.3389/fnhum.2014.00899. eCollection 2014. No abstract available.
Zaehle T, Rach S, Herrmann CS Transcranial alternating current stimulation enhances individual alpha activity in human EEG. PLoS One. 2010 Nov 1;5(11):e13766. doi: 10.1371/journal.pone.0013766.
Therapeutic Effects of Transcranial Alternative Current Stimulation (tACS) in Chronic Post Stroke Hemianopia
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
