Bhavnani SP, Parakh K, Atreja A, Druz R, Graham GN, Hayek SS, Krumholz HM, Maddox TM, Majmudar MD, Rumsfeld JS, Shah BR 2017 Roadmap for Innovation-ACC Health Policy Statement on Healthcare Transformation in the Era of Digital Health, Big Data, and Precision Health: A Report of the American College of Cardiology Task Force on Health Policy Statements and Systems of Care. J Am Coll Cardiol. 2017 Nov 28;70(21):2696-2718. doi: 10.1016/j.jacc.2017.10.018. No abstract available.
Bonniface L, Green L Finding a new kind of knowledge on the HeartNET website. Health Info Libr J. 2007 Dec;24 Suppl 1:67-76. doi: 10.1111/j.1471-1842.2007.00742.x.
Bramley TJ, Gerbino PP, Nightengale BS, Frech-Tamas F Relationship of blood pressure control to adherence with antihypertensive monotherapy in 13 managed care organizations. J Manag Care Pharm. 2006 Apr;12(3):239-45. doi: 10.18553/jmcp.2006.12.3.239.
Cajita MI, Cajita TR, Han HR Health Literacy and Heart Failure: A Systematic Review. J Cardiovasc Nurs. 2016 Mar-Apr;31(2):121-30. doi: 10.1097/JCN.0000000000000229.
Chung ML, Moser DK, Lennie TA, Frazier SK Perceived social support predicted quality of life in patients with heart failure, but the effect is mediated by depressive symptoms. Qual Life Res. 2013 Sep;22(7):1555-63. doi: 10.1007/s11136-012-0294-4. Epub 2012 Oct 18.
Dekker RL Patient perspectives about depressive symptoms in heart failure: a review of the qualitative literature. J Cardiovasc Nurs. 2014 Jan-Feb;29(1):E9-15. doi: 10.1097/JCN.0b013e318273a5d6.
Evangelista LS, Shinnick MA What do we know about adherence and self-care? J Cardiovasc Nurs. 2008 May-Jun;23(3):250-7. doi: 10.1097/01.JCN.0000317428.98844.4d.
Gammon D, Strand M, Eng LS, Borosund E, Varsi C, Ruland C Shifting Practices Toward Recovery-Oriented Care Through an E-Recovery Portal in Community Mental Health Care: A Mixed-Methods Exploratory Study. J Med Internet Res. 2017 May 2;19(5):e145. doi: 10.2196/jmir.7524.
Green CP, Porter CB, Bresnahan DR, Spertus JA Development and evaluation of the Kansas City Cardiomyopathy Questionnaire: a new health status measure for heart failure. J Am Coll Cardiol. 2000 Apr;35(5):1245-55. doi: 10.1016/s0735-1097(00)00531-3.
Jaarsma T, Arestedt KF, Martensson J, Dracup K, Stromberg A The European Heart Failure Self-care Behaviour scale revised into a nine-item scale (EHFScB-9): a reliable and valid international instrument. Eur J Heart Fail. 2009 Jan;11(1):99-105. doi: 10.1093/eurjhf/hfn007.
Khaw KT, Wareham N, Bingham S, Welch A, Luben R, Day N Combined impact of health behaviours and mortality in men and women: the EPIC-Norfolk prospective population study. PLoS Med. 2008 Jan 8;5(1):e12. doi: 10.1371/journal.pmed.0050012. Erratum In: PLoS Med. 2008 Mar 18;5(3):e70.
Kroenke K, Spitzer RL, Williams JB, Lowe B The Patient Health Questionnaire Somatic, Anxiety, and Depressive Symptom Scales: a systematic review. Gen Hosp Psychiatry. 2010 Jul-Aug;32(4):345-59. doi: 10.1016/j.genhosppsych.2010.03.006. Epub 2010 May 7.
Lee KS, Lennie TA, Wu JR, Biddle MJ, Moser DK Depressive symptoms, health-related quality of life, and cardiac event-free survival in patients with heart failure: a mediation analysis. Qual Life Res. 2014 Aug;23(6):1869-76. doi: 10.1007/s11136-014-0636-5. Epub 2014 Feb 1.
Musekamp G, Schuler M, Seekatz B, Bengel J, Faller H, Meng K Does improvement in self-management skills predict improvement in quality of life and depressive symptoms? A prospective study in patients with heart failure up to one year after self-management education. BMC Cardiovasc Disord. 2017 Feb 15;17(1):51. doi: 10.1186/s12872-017-0486-5.
Rasmussen JN, Chong A, Alter DA Relationship between adherence to evidence-based pharmacotherapy and long-term mortality after acute myocardial infarction. JAMA. 2007 Jan 10;297(2):177-86. doi: 10.1001/jama.297.2.177.
Rutledge T, Reis VA, Linke SE, Greenberg BH, Mills PJ Depression in heart failure a meta-analytic review of prevalence, intervention effects, and associations with clinical outcomes. J Am Coll Cardiol. 2006 Oct 17;48(8):1527-37. doi: 10.1016/j.jacc.2006.06.055. Epub 2006 Sep 26.
Spitzer RL, Kroenke K, Williams JB, Lowe B A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med. 2006 May 22;166(10):1092-7. doi: 10.1001/archinte.166.10.1092.
Stogios N, Kaur B, Huszti E, Vasanthan J, Nolan RP Advancing Digital Health Interventions as a Clinically Applied Science for Blood Pressure Reduction: A Systematic Review and Meta-analysis. Can J Cardiol. 2020 May;36(5):764-774. doi: 10.1016/j.cjca.2019.11.010. Epub 2019 Nov 15.
Wu RC, Delgado D, Costigan J, Ross H, MacIver J Pilot study of an Internet patient-physician communication tool for heart failure disease management. World Hosp Health Serv. 2006;42(3):32-8.
Zou H, Chen Y, Fang W, Zhang Y, Fan X Identification of factors associated with self-care behaviors using the COM-B model in patients with chronic heart failure. Eur J Cardiovasc Nurs. 2017 Aug;16(6):530-538. doi: 10.1177/1474515117695722. Epub 2017 Feb 1.
Zou H, Chen Y, Fang W, Zhang Y, Fan X The mediation effect of health literacy between subjective social status and depressive symptoms in patients with heart failure. J Psychosom Res. 2016 Dec;91:33-39. doi: 10.1016/j.jpsychores.2016.10.006. Epub 2016 Oct 19.
ODYSSEE-vCHAT Pilot Trial: A Virtual Community Promoting Health Literacy, Self-Care, and Peer Support for Heart Failure
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.