Healthy — Study of Cerebral Activation by fNIRS During Vibration-induced Illusion of Movement in Healthy and Stroke Participants.
Citation(s)
Adamo DE, Scotland S, Martin BJ Upper limb kinesthetic asymmetries: gender and handedness effects. Neurosci Lett. 2012 May 16;516(2):188-92. doi: 10.1016/j.neulet.2012.03.077. Epub 2012 Apr 3.
Chancel M, Landelle C, Blanchard C, Felician O, Guerraz M, Kavounoudias A Hand movement illusions show changes in sensory reliance and preservation of multisensory integration with age for kinaesthesia. Neuropsychologia. 2018 Oct;119:45-58. doi: 10.1016/j.neuropsychologia.2018.07.027. Epub 2018 Jul 29.
Collins DF, Refshauge KM, Todd G, Gandevia SC Cutaneous receptors contribute to kinesthesia at the index finger, elbow, and knee. J Neurophysiol. 2005 Sep;94(3):1699-706. doi: 10.1152/jn.00191.2005. Epub 2005 May 25.
Gilhodes JC, Roll JP, Tardy-Gervet MF Perceptual and motor effects of agonist-antagonist muscle vibration in man. Exp Brain Res. 1986;61(2):395-402. doi: 10.1007/BF00239528.
Imai R, Hayashida K, Nakano H, Morioka S Brain Activity Associated with the Illusion of Motion Evoked by Different Vibration Stimulation Devices: An fNIRS Study. J Phys Ther Sci. 2014 Jul;26(7):1115-9. doi: 10.1589/jpts.26.1115. Epub 2014 Jul 30.
Kodama T, Nakano H, Ohsugi H, Murata S Effects of vibratory stimulation-induced kinesthetic illusions on the neural activities of patients with stroke. J Phys Ther Sci. 2016 Jan;28(2):419-25. doi: 10.1589/jpts.28.419. Epub 2016 Feb 29.
Proske U, Gandevia SC The proprioceptive senses: their roles in signaling body shape, body position and movement, and muscle force. Physiol Rev. 2012 Oct;92(4):1651-97. doi: 10.1152/physrev.00048.2011.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
