Healthy — Clinical Trial on Ceramic Partial Laminate Veneers With Different Luting Agents
Citation(s)
Ceinos R, Pouyssegur V, Allard Y, Bertrand MF Esthetic rehabilitation of the smile with partial laminate veneers in an older adult. Clin Case Rep. 2018 Jun 4;6(8):1407-1411. doi: 10.1002/ccr3.1593. eCollection 2018 Aug.
Gresnigt M, Ozcan M Esthetic rehabilitation of anterior teeth with porcelain laminates and sectional veneers. J Can Dent Assoc. 2011;77:b143.
Gresnigt MM, Kalk W, Ozcan M Randomized controlled split-mouth clinical trial of direct laminate veneers with two micro-hybrid resin composites. J Dent. 2012 Sep;40(9):766-75. doi: 10.1016/j.jdent.2012.05.010. Epub 2012 Jun 2.
Gresnigt MMM, Sugii MM, Johanns KBFW, van der Made SAM Comparison of conventional ceramic laminate veneers, partial laminate veneers and direct composite resin restorations in fracture strength after aging. J Mech Behav Biomed Mater. 2021 Feb;114:104172. doi: 10.1016/j.jmbbm.2020.104172. Epub 2020 Nov 4.
Horvath S, Schulz CP Minimally invasive restoration of a maxillary central incisor with a partial veneer. Eur J Esthet Dent. 2012 Spring;7(1):6-16.
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
