Head and Neck Cancer — Acupressure on Xerostomia in Head and Neck Cancer Patients
Citation(s)
Aarstad HJ, Osthus AA, Aarstad HH, Lybak S, Aarstad AKH EORTC Quality of Life Questionnaire Head and Neck (H&N)-35 scores from H&N squamous cell carcinoma patients obtained at diagnosis and at 6, 9 and 12 months following diagnosis predict 10-year overall survival. Eur Arch Otorhinolaryngol. 2019 Dec;276(12):3495-3505. doi: 10.1007/s00405-019-05630-2. Epub 2019 Sep 16.
Assery MKA Efficacy of Artificial Salivary Substitutes in Treatment of Xerostomia: A Systematic Review. J Pharm Bioallied Sci. 2019 Feb;11(Suppl 1):S1-S12. doi: 10.4103/jpbs.JPBS_220_18.
Assy Z, Brand HS A systematic review of the effects of acupuncture on xerostomia and hyposalivation. BMC Complement Altern Med. 2018 Feb 13;18(1):57. doi: 10.1186/s12906-018-2124-x.
Bhide SA, Miah AB, Harrington KJ, Newbold KL, Nutting CM Radiation-induced xerostomia: pathophysiology, prevention and treatment. Clin Oncol (R Coll Radiol). 2009 Dec;21(10):737-44. doi: 10.1016/j.clon.2009.09.002. Epub 2009 Oct 14.
Bjordal K, Ahlner-Elmqvist M, Tollesson E, Jensen AB, Razavi D, Maher EJ, Kaasa S Development of a European Organization for Research and Treatment of Cancer (EORTC) questionnaire module to be used in quality of life assessments in head and neck cancer patients. EORTC Quality of Life Study Group. Acta Oncol. 1994;33(8):879-85. doi: 10.3109/02841869409098450.
Braga FP, Lemos Junior CA, Alves FA, Migliari DA Acupuncture for the prevention of radiation-induced xerostomia in patients with head and neck cancer. Braz Oral Res. 2011 Mar-Apr;25(2):180-5. doi: 10.1590/s1806-83242011000200014.
Bustillos H, Indorf A, Alwan L, Thompson J, Jung L Xerostomia: an immunotherapy-related adverse effect in cancer patients. Support Care Cancer. 2022 Feb;30(2):1681-1687. doi: 10.1007/s00520-021-06535-9. Epub 2021 Sep 25.
Chambers MS, Garden AS, Kies MS, Martin JW Radiation-induced xerostomia in patients with head and neck cancer: pathogenesis, impact on quality of life, and management. Head Neck. 2004 Sep;26(9):796-807. doi: 10.1002/hed.20045.
Cheng CQ, Xu H, Liu L, Wang RN, Liu YT, Li J, Zhou XK Efficacy and safety of pilocarpine for radiation-induced xerostomia in patients with head and neck cancer: A systematic review and meta-analysis. J Am Dent Assoc. 2016 Apr;147(4):236-43. doi: 10.1016/j.adaj.2015.09.014. Epub 2015 Nov 10.
Cheng HL, Yeung WF, Wong HF, Lo HT, Molassiotis A Self-Acupressure for Symptom Management in Cancer Patients: A Systematic Review. J Pain Symptom Manage. 2023 Jul;66(1):e109-e128. doi: 10.1016/j.jpainsymman.2023.03.002. Epub 2023 Mar 9.
Cheung DST, Xu X, Smith R, Takemura N, Yeung WF, Chan WL, Lao L, Lin CC Invasive or noninvasive? A systematic review and network meta-analysis of acupuncture and acupressure to treat sleep disturbance in cancer patients. Worldviews Evid Based Nurs. 2023 Jun;20(3):202-211. doi: 10.1111/wvn.12617. Epub 2022 Dec 21.
Cheung DST, Yeung WF, Chau PH, Lam TC, Yang M, Lai K, Ip CY, Lao L, Lin CC Patient-centred, self-administered acupressure for Chinese advanced cancer patients experiencing fatigue and co-occurring symptoms: A pilot randomised controlled trial. Eur J Cancer Care (Engl). 2022 Sep;31(5):e13314. doi: 10.1111/ecc.13314. Epub 2020 Sep 7.
Davies AN A comparison of artificial saliva and chewing gum in the management of xerostomia in patients with advanced cancer. Palliat Med. 2000 May;14(3):197-203. doi: 10.1191/026921600672294077.
de Sousa TR, Mattos S, Marcon G, Furtado T, Duarte da Silva M Acupuncture techniques and acupoints used in individuals under chemotherapy or radiotherapy treatment of cancer: A systematic review. J Clin Nurs. 2023 Oct;32(19-20):6917-6933. doi: 10.1111/jocn.16812. Epub 2023 Jun 29.
Dirix P, Nuyts S, Vander Poorten V, Delaere P, Van den Bogaert W The influence of xerostomia after radiotherapy on quality of life: results of a questionnaire in head and neck cancer. Support Care Cancer. 2008 Feb;16(2):171-9. doi: 10.1007/s00520-007-0300-5. Epub 2007 Jul 6.
Eisbruch A, Kim HM, Terrell JE, Marsh LH, Dawson LA, Ship JA Xerostomia and its predictors following parotid-sparing irradiation of head-and-neck cancer. Int J Radiat Oncol Biol Phys. 2001 Jul 1;50(3):695-704. doi: 10.1016/s0360-3016(01)01512-7.
EORTC European Organisation for Research and Treatment of Cancer Quality of life-head and neck cancer 1994 [cited 2023 Dec]; Available from: https://www.eortc.org/app/uploads/sites/2/2018/08/Specimen-HN35-English.pdf.
Hahnel S, Behr M, Handel G, Burgers R Saliva substitutes for the treatment of radiation-induced xerostomia--a review. Support Care Cancer. 2009 Nov;17(11):1331-43. doi: 10.1007/s00520-009-0671-x. Epub 2009 Jun 4.
He Y, Guo X, May BH, Zhang AL, Liu Y, Lu C, Mao JJ, Xue CC, Zhang H Clinical Evidence for Association of Acupuncture and Acupressure With Improved Cancer Pain: A Systematic Review and Meta-Analysis. JAMA Oncol. 2020 Feb 1;6(2):271-278. doi: 10.1001/jamaoncol.2019.5233.
Kahn ST, Johnstone PA Management of xerostomia related to radiotherapy for head and neck cancer. Oncology (Williston Park). 2005 Dec;19(14):1827-32; discussion 1832-4, 1837-9.
Liu G, Qiu X, Tan X, Miao R, Tian W, Jing W Efficacy of a 1% malic acid spray for xerostomia treatment: A systematic review and meta-analysis. Oral Dis. 2023 Apr;29(3):862-872. doi: 10.1111/odi.14116. Epub 2022 Jan 17.
Mao JJ, Xie SX, Bowman MA Uncovering the expectancy effect: the validation of the acupuncture expectancy scale. Altern Ther Health Med. 2010 Nov-Dec;16(6):22-7.
Momm F, Volegova-Neher NJ, Schulte-Monting J, Guttenberger R Different saliva substitutes for treatment of xerostomia following radiotherapy. A prospective crossover study. Strahlenther Onkol. 2005 Apr;181(4):231-6. doi: 10.1007/s00066-005-1333-7.
Ni X, Tian T, Chen D, Liu L, Li X, Li F, Liang F, Zhao L Acupuncture for Radiation-Induced Xerostomia in Cancer Patients: A Systematic Review and Meta-Analysis. Integr Cancer Ther. 2020 Jan-Dec;19:1534735420980825. doi: 10.1177/1534735420980825.
Porter SR, Scully C, Hegarty AM An update of the etiology and management of xerostomia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Jan;97(1):28-46. doi: 10.1016/j.tripleo.2003.07.010.
Riley P, Glenny AM, Hua F, Worthington HV Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy. Cochrane Database Syst Rev. 2017 Jul 31;7(7):CD012744. doi: 10.1002/14651858.CD012744.
Walsh M, Fagan N, Davies A Xerostomia in patients with advanced cancer: a scoping review of clinical features and complications. BMC Palliat Care. 2023 Nov 11;22(1):178. doi: 10.1186/s12904-023-01276-4.
Yang WF, Liao GQ, Hakim SG, Ouyang DQ, Ringash J, Su YX Is Pilocarpine Effective in Preventing Radiation-Induced Xerostomia? A Systematic Review and Meta-analysis. Int J Radiat Oncol Biol Phys. 2016 Mar 1;94(3):503-11. doi: 10.1016/j.ijrobp.2015.11.012. Epub 2015 Nov 10.
Effect of Self-administered Acupressure for Improving Xerostomia in Head and Neck Cancer Patients: a Randomized Controlled Trial
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.