Clinical trial NCT02697305 - References

Glucose Metabolism Disorders — Incretin Effects of Branched Chain Amino Acids

Citation(s)

•   Berger S, Vongaraya N
  Insulin response to ingested protein in diabetes. Diabetes. 1966 May;15(5):303-6.
•   Calbet JA, MacLean DA
  Plasma glucagon and insulin responses depend on the rate of appearance of amino acids after ingestion of different protein solutions in humans. J Nutr. 2002 Aug;132(8):2174-82.
•   Chen Q, Reimer RA
  Dairy protein and leucine alter GLP-1 release and mRNA of genes involved in intestinal lipid metabolism in vitro. Nutrition. 2009 Mar;25(3):340-9. doi: 10.1016/j.nut.2008.08.012. Epub 2008 Nov 26.
•   ELRICK H, STIMMLER L, HLAD CJ Jr, ARAI Y
  PLASMA INSULIN RESPONSE TO ORAL AND INTRAVENOUS GLUCOSE ADMINISTRATION. J Clin Endocrinol Metab. 1964 Oct;24:1076-82.
•   Floyd JC Jr, Fajans SS, Conn JW, Knopf RF, Rull J
  Stimulation of insulin secretion by amino acids. J Clin Invest. 1966 Sep;45(9):1487-502.
•   Frid AH, Nilsson M, Holst JJ, Björck IM
  Effect of whey on blood glucose and insulin responses to composite breakfast and lunch meals in type 2 diabetic subjects. Am J Clin Nutr. 2005 Jul;82(1):69-75.
•   Gannon MC, Nuttall FQ
  Amino acid ingestion and glucose metabolism--a review. IUBMB Life. 2010 Sep;62(9):660-8. doi: 10.1002/iub.375. Review.
•   Gunnerud U, Holst JJ, Östman E, Björck I
  The glycemic, insulinemic and plasma amino acid responses to equi-carbohydrate milk meals, a pilot- study of bovine and human milk. Nutr J. 2012 Oct 12;11:83. doi: 10.1186/1475-2891-11-83.
•   Layman DK
  The role of leucine in weight loss diets and glucose homeostasis. J Nutr. 2003 Jan;133(1):261S-267S. Review.
•   Marina AS, Kutina AV, Shakhmatova EI, Balbotkina EV, Natochin YV
  Stimulation of glucagon-like peptide-1 secretion by water loading in human. Dokl Biol Sci. 2014 Nov;459:323-5. doi: 10.1134/S0012496614060027. Epub 2015 Jan 6.
•   Nauck MA, Homberger E, Siegel EG, Allen RC, Eaton RP, Ebert R, Creutzfeldt W
  Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses. J Clin Endocrinol Metab. 1986 Aug;63(2):492-8.
•   Nilsson M, Holst JJ, Björck IM
  Metabolic effects of amino acid mixtures and whey protein in healthy subjects: studies using glucose-equivalent drinks. Am J Clin Nutr. 2007 Apr;85(4):996-1004.
•   Nilsson M, Stenberg M, Frid AH, Holst JJ, Björck IM
  Glycemia and insulinemia in healthy subjects after lactose-equivalent meals of milk and other food proteins: the role of plasma amino acids and incretins. Am J Clin Nutr. 2004 Nov;80(5):1246-53.
•   Pal S, Ellis V
  The acute effects of four protein meals on insulin, glucose, appetite and energy intake in lean men. Br J Nutr. 2010 Oct;104(8):1241-8. doi: 10.1017/S0007114510001911. Epub 2010 May 11.
•   Palmer JP, Benson JW, Walter RM, Ensinck JW
  Arginine-stimulated acute phase of insulin and glucagon secretion in diabetic subjects. J Clin Invest. 1976 Sep;58(3):565-70.
•   Pedroso JA, Zampieri TT, Donato J Jr
  Reviewing the Effects of L-Leucine Supplementation in the Regulation of Food Intake, Energy Balance, and Glucose Homeostasis. Nutrients. 2015 May 22;7(5):3914-37. doi: 10.3390/nu7053914. Review.
•   Raptis S, Dollinger HC, Schröder KE, Schleyer M, Rothenbuchner G, Pfeiffer EF
  Differences in insulin, growth hormone and pancreatic enzyme secretion after intravenous and intraduodenal administration of mixed amino acids in man. N Engl J Med. 1973 Jun 7;288(23):1199-202.
•   Rocha DM, Faloona GR, Unger RH
  Glucagon-stimulating activity of 20 amino acids in dogs. J Clin Invest. 1972 Sep;51(9):2346-51.
•   Salehi A, Gunnerud U, Muhammed SJ, Ostman E, Holst JJ, Björck I, Rorsman P
  The insulinogenic effect of whey protein is partially mediated by a direct effect of amino acids and GIP on ß-cells. Nutr Metab (Lond). 2012 May 30;9(1):48. doi: 10.1186/1743-7075-9-48.
•   Solerte SB, Fioravanti M, Locatelli E, Bonacasa R, Zamboni M, Basso C, Mazzoleni A, Mansi V, Geroutis N, Gazzaruso C
  Improvement of blood glucose control and insulin sensitivity during a long-term (60 weeks) randomized study with amino acid dietary supplements in elderly subjects with type 2 diabetes mellitus. Am J Cardiol. 2008 Jun 2;101(11A):82E-88E. doi: 10.1016/j.amjcard.2008.03.006.
•   Tuma P, Gojda J
  Rapid determination of branched chain amino acids in human blood plasma by pressure-assisted capillary electrophoresis with contactless conductivity detection. Electrophoresis. 2015 Aug;36(16):1969-75. doi: 10.1002/elps.201400585. Epub 2015 Apr 8.
•   Tuma P
  Rapid determination of globin chains in red blood cells by capillary electrophoresis using INSTCoated fused-silica capillary. J Sep Sci. 2014 Apr;37(8):1026-32. doi: 10.1002/jssc.201400044. Epub 2014 Mar 13.
•   Vahl TP, Drazen DL, Seeley RJ, D'Alessio DA, Woods SC
  Meal-anticipatory glucagon-like peptide-1 secretion in rats. Endocrinology. 2010 Feb;151(2):569-75. doi: 10.1210/en.2009-1002. Epub 2009 Nov 13.
•   van Loon LJ, Kruijshoop M, Menheere PP, Wagenmakers AJ, Saris WH, Keizer HA
  Amino acid ingestion strongly enhances insulin secretion in patients with long-term type 2 diabetes. Diabetes Care. 2003 Mar;26(3):625-30.
•   Wahren J, Felig P, Hagenfeldt L
  Effect of protein ingestion on splanchnic and leg metabolism in normal man and in patients with diabetes mellitus. J Clin Invest. 1976 Apr;57(4):987-99.
•   Yang J, Chi Y, Burkhardt BR, Guan Y, Wolf BA
  Leucine metabolism in regulation of insulin secretion from pancreatic beta cells. Nutr Rev. 2010 May;68(5):270-9. doi: 10.1111/j.1753-4887.2010.00282.x. Review.
•   Yang J, Wong RK, Park M, Wu J, Cook JR, York DA, Deng S, Markmann J, Naji A, Wolf BA, Gao Z
  Leucine regulation of glucokinase and ATP synthase sensitizes glucose-induced insulin secretion in pancreatic beta-cells. Diabetes. 2006 Jan;55(1):193-201.

Effect of Intravenously and Orally Administered Branched Chain Amino Acids on Incretin Response

Details for clinical trial NCT02697305