Fibromyalgia — Exercise, Irritable Bowel Syndrome and Fibromyalgia
Citation(s)
Akkaya N, Akkaya S, Atalay NS, Balci CS, Sahin F Relationship between the body image and level of pain, functional status, severity of depression, and quality of life in patients with fibromyalgia syndrome. Clin Rheumatol. 2012 Jun;31(6):983-8. doi: 10.1007/s10067-012-1965-9. Epub 2012 Mar 7.
Barsky AJ, Borus JF Functional somatic syndromes. Ann Intern Med. 1999 Jun 1;130(11):910-21. doi: 10.7326/0003-4819-130-11-199906010-00016.
Clauw DJ Fibromyalgia: a clinical review. JAMA. 2014 Apr 16;311(15):1547-55. doi: 10.1001/jama.2014.3266.
Johannesson E, Jakobsson Ung E, Sadik R, Ringstrom G Experiences of the effects of physical activity in persons with irritable bowel syndrome (IBS): a qualitative content analysis. Scand J Gastroenterol. 2018 Oct-Nov;53(10-11):1194-1200. doi: 10.1080/00365521.2018.1519596. Epub 2018 Nov 25.
Jones KD, Clark SR, Bennett RM Prescribing exercise for people with fibromyalgia. AACN Clin Issues. 2002 May;13(2):277-93. doi: 10.1097/00044067-200205000-00012.
Kim YS Why should gastroenterologists know about fibromyalgia? Common pathogenesis and clinical implications. J Neurogastroenterol Motil. 2011 Jan;17(1):1-3. doi: 10.5056/jnm.2011.17.1.1. Epub 2011 Jan 26. No abstract available.
Kingsley JD, McMillan V, Figueroa A The effects of 12 weeks of resistance exercise training on disease severity and autonomic modulation at rest and after acute leg resistance exercise in women with fibromyalgia. Arch Phys Med Rehabil. 2010 Oct;91(10):1551-7. doi: 10.1016/j.apmr.2010.07.003.
Linsalata M, Riezzo G, D'Attoma B, Clemente C, Orlando A, Russo F Noninvasive biomarkers of gut barrier function identify two subtypes of patients suffering from diarrhoea predominant-IBS: a case-control study. BMC Gastroenterol. 2018 Nov 6;18(1):167. doi: 10.1186/s12876-018-0888-6.
Mannerkorpi K, Iversen MD Physical exercise in fibromyalgia and related syndromes. Best Pract Res Clin Rheumatol. 2003 Aug;17(4):629-47. doi: 10.1016/s1521-6942(03)00038-x.
Martinez-Lavin M Biology and therapy of fibromyalgia. Stress, the stress response system, and fibromyalgia. Arthritis Res Ther. 2007;9(4):216. doi: 10.1186/ar2146.
Rooks DS Talking to patients with fibromyalgia about physical activity and exercise. Curr Opin Rheumatol. 2008 Mar;20(2):208-12. doi: 10.1097/BOR.0b013e3282f5687a.
Russo F, Riezzo G, Orlando A, Linsalata M, D'Attoma B, Prospero L, Ignazzi A, Giannelli G A Comparison of the Low-FODMAPs Diet and a Tritordeum-Based Diet on the Gastrointestinal Symptom Profile of Patients Suffering from Irritable Bowel Syndrome-Diarrhea Variant (IBS-D): A Randomized Controlled Trial. Nutrients. 2022 Apr 8;14(8):1544. doi: 10.3390/nu14081544.
Sarzi-Puttini P, Giorgi V, Marotto D, Atzeni F Fibromyalgia: an update on clinical characteristics, aetiopathogenesis and treatment. Nat Rev Rheumatol. 2020 Nov;16(11):645-660. doi: 10.1038/s41584-020-00506-w. Epub 2020 Oct 6.
Tanaka H, Monahan KD, Seals DR Age-predicted maximal heart rate revisited. J Am Coll Cardiol. 2001 Jan;37(1):153-6. doi: 10.1016/s0735-1097(00)01054-8.
Valkeinen H, Alen M, Hannonen P, Hakkinen A, Airaksinen O, Hakkinen K Changes in knee extension and flexion force, EMG and functional capacity during strength training in older females with fibromyalgia and healthy controls. Rheumatology (Oxford). 2004 Feb;43(2):225-8. doi: 10.1093/rheumatology/keh027. Epub 2003 Sep 16.
Valkeinen H, Hakkinen A, Hannonen P, Hakkinen K, Alen M Acute heavy-resistance exercise-induced pain and neuromuscular fatigue in elderly women with fibromyalgia and in healthy controls: effects of strength training. Arthritis Rheum. 2006 Apr;54(4):1334-9. doi: 10.1002/art.21751.
Wilson RC, Jones PW A comparison of the visual analogue scale and modified Borg scale for the measurement of dyspnoea during exercise. Clin Sci (Lond). 1989 Mar;76(3):277-82. doi: 10.1042/cs0760277.
Effects of Indoor Activity on the Integrity and Function of the Intestinal Barrier of Patients With Fibromyalgia and Irritable Bowel Syndrome
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.
