Ayta IA, McKinlay JB, Krane RJ The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int. 1999 Jul;84(1):50-6. doi: 10.1046/j.1464-410x.1999.00142.x.
Bahren W, Gall H, Scherb W, Stief C, Thon W Arterial anatomy and arteriographic diagnosis of arteriogenic impotence. Cardiovasc Intervent Radiol. 1988 Aug;11(4):195-210. doi: 10.1007/BF02577004.
Billups KL, Bank AJ, Padma-Nathan H, Katz S, Williams R Erectile dysfunction is a marker for cardiovascular disease: results of the minority health institute expert advisory panel. J Sex Med. 2005 Jan;2(1):40-50; discussion 50-2. doi: 10.1111/j.1743-6109.2005.20104_1.x.
Dewar ML, Blundell PE, Lidstone D, Herba MJ, Chiu RC Effects of abdominal aneurysmectomy, aortoiliac bypass grafting and angioplasty on male sexual potency: a prospective study. Can J Surg. 1985 Mar;28(2):154-6, 159.
Ginestie J, Romieu A [The treatment of impotence of vascular origin. Revascularisation of the corpora cavernosa]. J Urol Nephrol (Paris). 1976 Oct-Nov;82(10-11):853-9. French.
Giuliano FA, Leriche A, Jaudinot EO, de Gendre AS Prevalence of erectile dysfunction among 7689 patients with diabetes or hypertension, or both. Urology. 2004 Dec;64(6):1196-201. doi: 10.1016/j.urology.2004.08.059.
Goldwasser B, Carson CC 3rd, Braun SD, McCann RL Impotence due to the pelvic steal syndrome: treatment by iliac transluminal angioplasty. J Urol. 1985 May;133(5):860-1. doi: 10.1016/s0022-5347(17)49258-5. No abstract available.
Gupta BP, Murad MH, Clifton MM, Prokop L, Nehra A, Kopecky SL The effect of lifestyle modification and cardiovascular risk factor reduction on erectile dysfunction: a systematic review and meta-analysis. Arch Intern Med. 2011 Nov 14;171(20):1797-803. doi: 10.1001/archinternmed.2011.440. Epub 2011 Sep 12.
Hall SA, Shackelton R, Rosen RC, Araujo AB Sexual activity, erectile dysfunction, and incident cardiovascular events. Am J Cardiol. 2010 Jan 15;105(2):192-7. doi: 10.1016/j.amjcard.2009.08.671.
Hauri D Penile revascularization surgery in erectile dysfunction. Urol Int. 2003;70(2):132-40. doi: 10.1159/000068187.
Herman A, Adar R, Rubinstein Z Vascular lesions associated with impotence in diabetic and nondiabetic arterial occlusive disease. Diabetes. 1978 Oct;27(10):975-81. doi: 10.2337/diab.27.10.975.
Hodges LD, Kirby M, Solanki J, O'Donnell J, Brodie DA The temporal relationship between erectile dysfunction and cardiovascular disease. Int J Clin Pract. 2007 Dec;61(12):2019-25. doi: 10.1111/j.1742-1241.2007.01629.x.
Lue TF, Tanagho EA Physiology of erection and pharmacological management of impotence. J Urol. 1987 May;137(5):829-36. doi: 10.1016/s0022-5347(17)44267-4. No abstract available.
Lue TF Erectile dysfunction. N Engl J Med. 2000 Jun 15;342(24):1802-13. doi: 10.1056/NEJM200006153422407. No abstract available.
Lue TF Physiology of penile erection and pathophysiology of erectile dysfunction. In: Saunders W, editor Campbell-Walsh Urology. Philadelphia, 2012.
Marma AK, Berry JD, Ning H, Persell SD, Lloyd-Jones DM Distribution of 10-year and lifetime predicted risks for cardiovascular disease in US adults: findings from the National Health and Nutrition Examination Survey 2003 to 2006. Circ Cardiovasc Qual Outcomes. 2010 Jan;3(1):8-14. doi: 10.1161/CIRCOUTCOMES.109.869727. Epub 2009 Nov 16.
Moreira ED Jr, Lbo CF, Diament A, Nicolosi A, Glasser DB Incidence of erectile dysfunction in men 40 to 69 years old: results from a population-based cohort study in Brazil. Urology. 2003 Feb;61(2):431-6. doi: 10.1016/s0090-4295(02)02158-1.
Schouten BW, Bosch JL, Bernsen RM, Blanker MH, Thomas S, Bohnen AM Incidence rates of erectile dysfunction in the Dutch general population. Effects of definition, clinical relevance and duration of follow-up in the Krimpen Study. Int J Impot Res. 2005 Jan-Feb;17(1):58-62. doi: 10.1038/sj.ijir.3901264.
Shamloul R, Ghanem H Erectile dysfunction. Lancet. 2013 Jan 12;381(9861):153-65. doi: 10.1016/S0140-6736(12)60520-0. Epub 2012 Oct 5.
Shishehbor MH, Philip F Endovascular treatment for erectile dysfunction: an old paradigm revisited. J Am Coll Cardiol. 2012 Dec 25;60(25):2628-30. doi: 10.1016/j.jacc.2012.09.032. Epub 2012 Nov 21. No abstract available.
Solomon H, Man JW, Wierzbicki AS, Jackson G Relation of erectile dysfunction to angiographic coronary artery disease. Am J Cardiol. 2003 Jan 15;91(2):230-1. doi: 10.1016/s0002-9149(02)03113-2. No abstract available.
Takimura CK, Galon MZ, Gutierrez PS, Sojitra P, Vyas A, Doshi M, Lemos PA A new polymer-free drug-eluting stent with nanocarriers eluting sirolimus from stent-plus-balloon compared with bare-metal stent and with biolimus A9 eluting stent in porcine coronary arteries. Cardiovasc Diagn Ther. 2015 Apr;5(2):113-21. doi: 10.3978/j.issn.2223-3652.2015.03.08.
Valji K, Bookstein JJ Transluminal angioplasty in the treatment of arteriogenic impotence. Cardiovasc Intervent Radiol. 1988 Aug;11(4):245-52. doi: 10.1007/BF02577011.
Van Unnik JG, Marsman JW Impotence due to the external iliac steal syndrome treated by percutaneous transluminal angioplasty. J Urol. 1984 Mar;131(3):544-5. doi: 10.1016/s0022-5347(17)50490-5.
Wang T, Lee W, Chen W, Chen M Comprehensive assessment of prevalence and distribution of obstructive pelvic arterial lesions by computed tomographic angiography in patients with erectile dysfunction. American College of Cardiology. San Francisco: Elsevier, 2013:B160.
Wang TD, Lee WJ, Yang SC, Lin PC, Tai HC, Liu SP, Huang CH, Chen WJ, Chen MF, Hsieh JT Clinical and Imaging Outcomes up to 1 Year Following Balloon Angioplasty for Isolated Penile Artery Stenoses in Patients With Erectile Dysfunction: The PERFECT-2 Study. J Endovasc Ther. 2016 Dec;23(6):867-877. doi: 10.1177/1526602816669337. Epub 2016 Sep 14.
Sirolimus Eluting Balloon Utilization for Treatment of Vasculogenic Erectile Dysfunction - The SUASION Study
Interventional studies are often prospective and are specifically tailored to evaluate direct impacts of treatment or preventive measures on disease.
Observational studies are often retrospective and are used to assess potential causation in exposure-outcome relationships and therefore influence preventive methods.
Expanded access is a means by which manufacturers make investigational new drugs available, under certain circumstances, to treat a patient(s) with a serious disease or condition who cannot participate in a controlled clinical trial.
Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.
Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.