NCT04266990 - Clinical Trial References

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Citation(s)

Brown SW, Goldstein LH
Can Seizure-Alert Dogs predict seizures? Epilepsy Res. 2011 Dec;97(3):236-42. doi: 10.1016/j.eplepsyres.2011.10.019. Epub 2011 Nov 1.
Edney AT
Dogs and human epilepsy. Vet Rec. 1993 Apr 3;132(14):337-8. doi: 10.1136/vr.132.14.337. No abstract available.
Rooney NJ, Morant S, Guest C
Investigation into the value of trained glycaemia alert dogs to clients with type I diabetes. PLoS One. 2013 Aug 7;8(8):e69921. doi: 10.1371/journal.pone.0069921. eCollection 2013.
Schmidt K, Podmore I
Current Challenges in Volatile Organic Compounds Analysis as Potential Biomarkers of Cancer. J Biomark. 2015;2015:981458. doi: 10.1155/2015/981458. Epub 2015 Mar 30.
Wells DL, Lawson SW, Siriwardena AN
Canine responses to hypoglycemia in patients with type 1 diabetes. J Altern Complement Med. 2008 Dec;14(10):1235-41. doi: 10.1089/acm.2008.0288.
Willis, C
M.., 2005. Olfactory detection of human bladder cancer by dogs: proof of principle study. Urologic Oncology: Seminars and Original Investigations, 23(3), p.217. Available at: http://linkinghub.elsevier.com/retrieve/pii/S1078143905000323.

Investigation of Behaviour by Dogs Prior to Human Epileptic Seizures and Potential Underlying Mechanisms. Part III: Olfactive Discriminative Ability of Dogs When Confronted With Seizure and Non-seizure Samples Part IV: Identification of Potential Biomarkers for Epilepsy in Human Sweat.

Details for clinical trial NCT04266990

Clinical trial NCT04266990 - References